Figure 6.

Independent Transcriptional Activity of hMuDR Elements Is Conferred by Evolutionarily Diverged Promoters.

(A) Gel-purified RT-PCR products corresponding to the MuDR region 4086 to 4722 were digested with AlwNI and analyzed by DNA gel blot analysis. The positions and compositions of three resulting products are indicated.

(B) The epigenetic status of hMuDR promoters was analyzed by DNA gel blot hybridization after FspI digestion of genomic DNA from two MuDR⁻ lines (lanes 1 and 2) and two MuDR⁺ lines (lanes 3 and 4), as described in the legend to Figure 1.