Table 1.
Specificity of the AgMaT1 Mannitol Carrier a
| Added Compound | Absorption (%) |
|---|---|
| None | 100 |
| 50 μM CCCP | 14.5 ± 1.4 |
| 100 μM PCMBS | 71.6 ± 8.1 |
| Mannitol | 14.1 ± 7.1 |
| Dulcitol | 60.5 ± 6.6 |
| Sorbitol | 43.6 ± 11.0 |
| Xylitol | 41.2 ± 4.2 |
| Myo-inositol | 50.5 ± 4.9 |
| Mannose | 66.0 ± 7.5 |
| Sucrose | 86.6 ± 4.9 |
| Glucose | 22.4 ± 6.6 |
| Fructose | 35.4 ± 5.3 |
a
Culture of MaDH4 expressing AgMaT1 and uptake conditions are as given in Figure 3 with an incubation time of 2 min. Inhibitors (at the indicated concentration), sugars, and polyols (5.5 mM) were added 30 sec before labelled mannitol. The results are the mean ±sd of three independent experiments (four replicates per experiment).