Table 3.
Baseline characteristics of the study population for the association between IR trajectories and cardiovascular disease based on the ELSA database
| Variables | Overall(n = 2740) | non-CVD(n = 2380) | CVD(n = 360) | P |
|---|---|---|---|---|
| Weight | 76.5 (14.3) | 76.3 (14.2) | 77.4 (14.9) | 0.176 |
| Height | 1.7 (0.1) | 1.7 (0.1) | 1.7 (0.1) | 0.072 |
| WC | 94.4 (12.1) | 94.2 (12.0) | 95.9 (12.5) | 0.011 |
| BMI | 27.7 (4.2) | 27.6 (4.2) | 28.3 (4.4) | 0.002 |
| HbA1c | 5.5 (0.6) | 5.5 (0.5) | 5.6 (0.7) | < 0.001 |
| Age | 63.5 (7.9) | 62.9 (7.7) | 67.5 (8.0) | < 0.001 |
| Gender (%) | ||||
| Male | 1185 (43.2) | 1033 (43.4) | 152 (42.2) | 0.715 |
| Female | 1555 (56.8) | 1347 (56.6) | 208 (57.8) | |
| Education (%) | ||||
| Below high school | 900 (32.8) | 757 (31.8) | 143 (39.7) | 0.009 |
| High school or equivalent | 1382 (50.4) | 1214 (51.0) | 168 (46.7) | |
| College or above | 458 (16.7) | 409 (17.2) | 49 (13.6) | |
| Marital (%) | ||||
| Widowed/Divorced/Separated/Unmarrie | 727 (26.5) | 613 (25.8) | 114 (31.7) | 0.021 |
| Married/Cohabiting | 2013 (73.5) | 1767 (74.2) | 246 (68.3) | |
| Drink (%) | ||||
| NO | 197 ( 7.2) | 163 ( 6.8) | 34 ( 9.4) | 0.095 |
| Yes | 2543 (92.8) | 2217 (93.2) | 326 (90.6) | |
| Smoke (%) | ||||
| Never smoked | 1147 (41.9) | 1000 (42.0) | 147 (40.8) | 0.313 |
| Used to smoke | 1264 (46.1) | 1087 (45.7) | 177 (49.2) | |
| Currently smoke | 329 (12.0) | 293 (12.3) | 36 (10.0) | |
| TG | 1.8 (1.1) | 1.8 (1.1) | 1.8 (1.0) | 0.448 |
| TC | 6.0 (1.2) | 6.0 (1.2) | 6.0 (1.4) | 0.827 |
| CRP | 3.5 (5.8) | 3.4 (5.8) | 4.1 (5.4) | 0.029 |
| LDL | 3.7 (1.1) | 3.7 (1.1) | 3.7 (1.2) | 0.414 |
| HD | 1.6 (0.4) | 1.6 (0.4) | 1.5 (0.4) | 0.015 |
| Glucose | 5.1 (0.9) | 5.0 (0.9) | 5.1 (0.9) | 0.616 |
| SBP | 134.0 (16.7) | 133.5 (16.8) | 137.3 (15.6) | < 0.001 |
| DB | 76.3 (9.8) | 76.4 (9.8) | 75.7 (9.8) | 0.241 |
| Asthmae (%) | ||||
| NO | 2425 (88.5) | 2114 (88.8) | 311 (86.4) | 0.207 |
| Yes | 315 (11.5) | 266 (11.2) | 49 (13.6) | |
| Lung (%) | ||||
| NO | 2637 (96.2) | 2303 (96.8) | 334 (92.8) | < 0.001 |
| Yes | 103 ( 3.8) | 77 ( 3.2) | 26 ( 7.2) | |
| Arthre (%) | ||||
| NO | 1895 (69.2) | 1683 (70.7) | 212 (58.9) | < 0.001 |
| Yes | 845 (30.8) | 697 (29.3) | 148 (41.1) | |
| Cancer (%) | ||||
| NO | 2586 (94.4) | 2243 (94.2) | 343 (95.3) | 0.502 |
| Yes | 154 ( 5.6) | 137 ( 5.8) | 17 ( 4.7) | |
| Satisfaction (%) | ||||
| Not satisfied | 390 (14.2) | 330 (13.9) | 60 (16.7) | 0.181 |
| Satisfied | 2350 (85.8) | 2050 (86.1) | 300 (83.3) | |
| Depression (%) | ||||
| NO | 2392 (87.3) | 2091 (87.9) | 301 (83.6) | 0.03 |
| Yes | 348 (12.7) | 289 (12.1) | 59 (16.4) | |
| Sleep problem(%) | ||||
| NO | 1650 (60.2) | 1441 (60.5) | 209 (58.1) | 0.4 |
| Yes | 1090 (39.8) | 939 (39.5) | 151 (41.9) | |
| Physical activity (%) | ||||
| NO | 190 ( 6.9) | 153 ( 6.4) | 37 (10.3) | 0.01 |
| Yes | 2550 (93.1) | 2227 (93.6) | 323 (89.7) | |
| Income | 23191.0 (20734.1) | 23750.1 (21680.3) | 19494.5 (12221.4) | < 0.001 |
| Hemoglobin | 14.4 (1.3) | 14.4 (1.3) | 14.4 (1.4) | 0.857 |
| TyG_group (%) | ||||
| Trajectory 3 | 605 (22.1) | 537 (22.6) | 68 (18.9) | 0.089 |
| Trajectory 2 | 1944 (70.9) | 1685 (70.8) | 259 (71.9) | |
| Trajectory 1 | 191 ( 7.0) | 158 ( 6.6) | 33 ( 9.2) | |
| TyG-WC_group (%) | ||||
| Trajectory 2 | 657 (24.0) | 594 (25.0) | 63 (17.5) | 0.002 |
| Trajectory 3 | 1310 (47.8) | 1137 (47.8) | 173 (48.1) | |
| Trajectory 1 | 773 (28.2) | 649 (27.3) | 124 (34.4) | |
| TyG-WWI_group (%) | ||||
| Trajectory 3 | 340 (12.4) | 309 (13.0) | 31 ( 8.6) | < 0.001 |
| Trajectory 2 | 1395 (50.9) | 1232 (51.8) | 163 (45.3) | |
| Trajectory 1 | 1005 (36.7) | 839 (35.3) | 166 (46.1) | |
| TyG-BMI_group (%) | ||||
| Trajectory 2 | 778 (28.4) | 695 (29.2) | 83 (23.1) | 0.035 |
| Trajectory 1 | 1224 (44.7) | 1058 (44.5) | 166 (46.1) | |
| Trajectory 3 | 738 (26.9) | 627 (26.3) | 111 (30.8) | |
| TyG-ABSI_group (%) | ||||
| Trajectory 3 | 412 (15.0) | 371 (15.6) | 41 (11.4) | 0.01 |
| Trajectory 2 | 1391 (50.8) | 1218 (51.2) | 173 (48.1) | |
| Trajectory 1 | 937 (34.2) | 791 (33.2) | 146 (40.6) | |
| TyG-BRI_group (%) | ||||
| Trajectory 2 | 730 (26.6) | 655 (27.5) | 75 (20.8) | 0.001 |
| Trajectory 1 | 1268 (46.3) | 1106 (46.5) | 162 (45.0) | |
| Trajectory 3 | 742 (27.1) | 619 (26.0) | 123 (34.2) | |
| METS-IR_group (%) | ||||
| Trajectory 3 | 789 (28.8) | 706 (29.7) | 83 (23.1) | 0.004 |
| Trajectory 2 | 1199 (43.8) | 1044 (43.9) | 155 (43.1) | |
| Trajectory 1 | 752 (27.4) | 630 (26.5) | 122 (33.9) | |
| TyG-WHtR_group (%) | ||||
| Trajectory 2 | 642 (23.4) | 580 (24.4) | 62 (17.2) | < 0.001 |
| Trajectory 1 | 1328 (48.5) | 1165 (48.9) | 163 (45.3) | |
| Trajectory 3 | 770 (28.1) | 635 (26.7) | 135 (37.5) | |
| AIP_group (%) | ||||
| Trajectory 3 | 560 (20.4) | 504 (21.2) | 56 (15.6) | 0.024 |
| Trajectory 2 | 1909 (69.7) | 1649 (69.3) | 260 (72.2) | |
| Trajectory 1 | 271 ( 9.9) | 227 ( 9.5) | 44 (12.2) | |
| CTI_group (%) | ||||
| Trajectory 3 | 451 (16.5) | 416 (17.5) | 35 ( 9.7) | < 0.001 |
| Trajectory 2 | 1918 (70.0) | 1660 (69.7) | 258 (71.7) | |
| Trajectory 1 | 371 (13.5) | 304 (12.8) | 67 (18.6) | |
| CHG_group (%) | ||||
| Trajectory 3 | 438 (16.0) | 382 (16.1) | 56 (15.6) | 0.802 |
| Trajectory 2 | 1340 (48.9) | 1168 (49.1) | 172 (47.8) | |
| Trajectory 1 | 962 (35.1) | 830 (34.9) | 132 (36.7) |