Table 8.

Incremental predictive value of adding cuIR to risk prediction models for incident CVD

Model	C-index (95%CI)	P	AIC	IDI (95%CI)	P	NRI (95%CI)	P
Basic model	0.596 (0.578, 0.619)	Ref	12499.5	Ref	Ref	Ref	Ref
Basic model+cuTyG	0.603 (0.584, 0.627)	< 0.001	12488.1	0.0174 (0.0135, 0.0217)	< 0.001	0.0326 (− 0.0024, 0.0756)	0.109
Basic model+cuTyG-WC	0.614 (0.596, 0.638)	< 0.001	12465.2	0.0426 (0.0358, 0.0492)	< 0.001	0.0729 (0.0214, 0.1189)	0.003
Basic model+cuTyG-WWI	0.601 (0.583, 0.625)	< 0.001	12488.9	0.0171 (0.0134, 0.0212)	< 0.001	0.0195 (− 0.0176, 0.0599)	0.339
Basic model+cuTyG-BMI	0.613 (0.595, 0.637)	< 0.001	12467.7	0.0397 (0.033, 0.0461)	< 0.001	0.0661 (0.014, 0.1097)	0.007
Basic model+cuTyG-ABSI	0.608 (0.588, 0.631)	< 0.001	12477.9	0.0298 (0.0246, 0.0353)	< 0.001	0.0256 (− 0.0196, 0.0722)	0.276
Basic model+cuTyG-BRI	0.609 (0.591, 0.634)	< 0.001	12,472	0.0353 (0.0291, 0.0411)	< 0.001	0.0467 (− 0.0032, 0.0918)	0.058
Basic model+cuTyG-WHtR	0.61 (0.592, 0.634)	< 0.001	12471.6	0.0367 (0.0304, 0.0427)	< 0.001	0.051 (4e-04, 0.0981)	0.037
Basic model+cuMETS-IR	0.613 (0.595, 0.636)	< 0.001	12,469	0.0357 (0.0294, 0.0423)	< 0.001	0.057 (0.0076, 0.1055)	0.022
Basic model+cuAIP	0.605 (0.586, 0.628)	< 0.001	12484.8	0.0196 (0.0152, 0.0245)	< 0.001	0.0445 (0.0059, 0.0889)	0.036
Basic model+cuCTI	0.606 (0.588, 0.629)	< 0.001	12481.6	0.0256 (0.0206, 0.0305)	< 0.001	0.0475 (6e-04, 0.0899)	0.036
Basic model+cuCHG	0.61 (0.592, 0.633)	< 0.001	12477.9	0.0254 (0.0203, 0.0311)	< 0.001	0.0547 (0.0095, 0.0977)	0.012