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. 2026 Aug 26;17:1844013. doi: 10.3389/fphar.2026.1844013

FIGURE 6.

Panel A shows a dot plot comparing HSP90N gene expression in transcripts per million across multiple cancer types, with some cancer names highlighted in red. Panel B presents a box plot indicating significantly higher HSP90N expression in breast cancer tissues compared to normal tissue. Panel C contains two pathology slide images of tissue samples, with the right image displaying more brown coloration, suggesting higher protein expression. Panel D features a Kaplan-Meier survival curve demonstrating reduced survival probability in patients with high HSP90N expression. Panel E displays violin plots of HSP90N expression across different cancer stages, indicating variability and a statistically significant difference among stages.

HSP90AA1 Expression and Clinical Significance in Breast Cancer. (A) HSP90AA1 expression between tumor and normal tissues in multiple cancer types based on the GEPIA database. (B) Evaluation of HSP90AA1 protein levels in breast tumors and normal tissues using the GEPIA database. (C,D) HIC results for HSP90AA1 in breast tumors and normal tissues were analyzed using the HPA database. (E) The impact of HSP90AA1 expression level on prognosis was analyzed based on the KM PLOTTER database. (F) The GEPIA database was utilized to assess the expression level of HSP90AA1 across different stages of breast cancer. All the data analysis. *p < 0.05.