Table 1.
A 21–amino acid SOS3 binding sequence called the FISL motif was identified in SOS2. Other serine/threonine protein kinases appear to contain an FISL motif, with A, F, I, S, L, and F being conserved absolutely. The cDNAs for PKS2 to PKS8 were determined experimentally, and together with their predicted amino acid sequences, they have been submitted to GenBank.