Table 1.
Comparison of baseline characteristics between the two groups.
| Variables | Total (n = 511) | EOS group (n = 139) | Non-EOS group (n = 372) | P |
|---|---|---|---|---|
| Age, (years) | 78.00 (69.00, 84.00) | 77.00 (69.00, 82.00) | 78.00 (70.00, 84.00) | 0.202 |
| Gender, n (%) | 0.434 | |||
| Male | 419 (82.00) | 117 (84.17) | 302 (81.18) | |
| Female | 92 (18.00) | 22 (15.83) | 70 (18.82) | |
| Smoking status, n (%) | 0.306 | |||
| Current smoker | 121 (23.68) | 28 (20.14) | 93 (25.00) | |
| Former smoker | 318 (62.23) | 94 (67.63) | 224 (60.22) | |
| Never smoker | 72 (14.09) | 17 (12.23) | 55 (14.78) | |
| FVC, (L) | 2.08 (1.74, 2.62) | 2.12 (1.85, 2.64) | 2.07 (1.72, 2.59) | 0.385 |
| FEV1, (L) | 1.04 (0.78, 1.40) | 1.08 (0.84, 1.46) | 1.03 (0.75, 1.35) | 0.299 |
| FVC%pred, (%) | 64.70(16.08) | 66.94(126.741) | 41.40(15.71) | 0.153 |
| FEV1%pred, (%) | 41.90(31.00, 54.3) | 42.00(33.00,56.05) | 41.40(30.00,53.00) | 0.305 |
| FEV1/FVC, (%) | 50.00 (42.56, 59.00) | 50.79 (43.69, 60.70) | 50.00 (42.10, 58.00) | 0.459 |
| White blood cell count, (10^9/L) | 7.76 (6.00, 10.41) | 6.78 (5.46, 8.33) | 8.32 (6.22, 11.67) | <0.001 |
| Red blood cell count, (10^12/L) | 4.29 (3.87, 4.75) | 4.40 (3.84, 4.72) | 4.27 (3.88, 4.75) | 0.616 |
| Hematocrit, (L/L) | 0.40 (0.36, 0.44) | 0.40 (0.37, 0.44) | 0.40 (0.36, 0.44) | 0.738 |
| Hemoglobin, (g/L) | 131.00 (118.00, 144.00) | 133.00 (118.50, 143.50) | 131.00 (117.75, 145.00) | 0.891 |
| Platelets, (10^9/L) | 192.00 (153.00, 251.00) | 200.00 (156.00, 250.50) | 190.00 (153.00, 251.25) | 0.309 |
| Neutrophil count, (10^9/L) | 6.17 (4.36, 8.57) | 4.69 (3.59, 6.04) | 6.85 (4.79, 9.69) | <0.001 |
| Neutrophil percentage, (%) | 0.79 (0.71, 0.86) | 0.70 (0.62, 0.75) | 0.83 (0.76, 0.88) | <0.001 |
| Eosinophil count, (10^9/L) | 0.05 (0.00, 0.15) | 0.24 (0.17, 0.36) | 0.02 (0.00, 0.07) | < 0.001 |
| Eosinophil percentage | 0.60% (0.00, 2.10%) | 3.30% (2.50, 5.45%) | 0.20% (0.00, 0.80%) | < 0.001 |
| Lymphocyte count, (10^9/L) | 0.96 (0.63, 1.40) | 1.19 (0.88, 1.64) | 0.86 (0.57, 1.28) | <0.001 |
| Lymphocyte percentage, (%) | 0.13 (0.08, 0.19) | 0.18 (0.13, 0.25) | 0.11 (0.07, 0.16) | <0.001 |
| C-reactive protein, (mg/L) | 1.88 (0.56, 8.38) | 1.24 (0.37, 4.87) | 2.23 (0.70, 9.96) | 0.011 |
| Procalcitonin, (ng/mL) | 0.10 (0.05, 0.18) | 0.07 (0.04, 0.11) | 0.10 (0.05, 0.20) | <0.001 |
| D-Dimer, (ug/mL) | 0.29 (0.18, 0.61) | 0.25 (0.16, 0.52) | 0.32 (0.18, 0.66) | 0.026 |
| NT-proBNP, (pg/mL) | 482.00 (157.50, 1690.50) | 242.00 (85.50, 682.50) | 561.50 (218.50, 2120.25) | <0.001 |
| Hypertension, n (%) | 0.915 | |||
| No | 237 (46.38) | 65 (46.76) | 172 (46.24) | |
| Yes | 274 (53.62) | 74 (53.24) | 200 (53.76) | |
| Diabetes, n (%) | 0.875 | |||
| No | 402 (78.67) | 110 (79.14) | 292 (78.49) | |
| Yes | 109 (21.33) | 29 (20.86) | 80 (21.51) | |
| Heart failure, n (%) | 0.006 | |||
| No | 448 (87.67) | 131 (94.24) | 317 (85.22) | |
| Yes | 63 (12.33) | 8 (5.76) | 55 (14.78) | |
| Coronary heart disease, n (%) | 0.967 | |||
| No | 405 (79.26) | 110 (79.14) | 295 (79.30) | |
| Yes | 106 (20.74) | 29 (20.86) | 77 (20.70) | |
| Treatments during hospitalization | ||||
| Antibiotic use, n (%) | 0.730 | |||
| No | 7 (1.37) | 1 (0.72) | 6 (1.61) | |
| Yes | 504 (98.63) | 138 (99.28) | 366 (98.39) | |
| Systemic steroids, n (%) | 0.001 | |||
| No | 263 (51.47) | 88 (63.31) | 175 (47.04) | |
| Yes | 248 (48.53) | 51 (36.69) | 197 (52.96) | |
Data are presented as median (25th percentile, 75th percentile) or n (%). FVC, forced vital capacity; FEV₁, forced expiratory volume in 1 s; % predicted, percentage of the predicted value.