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. 2026 May 31;71(10):4756–4763. doi: 10.1007/s10620-026-10026-4

Table 2.

In-hospital outcomes of patients undergoing ERCP in the National Inpatient Sample (2016–2022), weighted for sample design, stratified by high-risk comorbidity status*

Outcome No high-risk comorbidity n = 904,234 High-risk comorbidity n = 267,739 p-value
Mortality 7,469 (0.8) 10,169 (3.8) < 0.001
Any morbidity 322,919 (35.7) 192,359 (71.8) < 0.001
 Neurological complication 7,939 (0.9) 7,339 (2.7) < 0.001
 Cardiovascular complication 76,694 (8.5) 76,174 (28.5) < 0.001
 Respiratory complication 36,024 (4.0) 38,544 (14.4) < 0.001
 Gastrointestinal complication 78,289 (8.7) 19,139 (7.1) < 0.001
 Infectious complication 131,944 (14.6) 82,019 (30.6) < 0.001
 Wound complication 32,369 (3.6) 31,849 (11.9) < 0.001
 Hematological complication 33,309 (3.7) 27,814 (10.4) < 0.001
 Venous thromboembolism 14,539 (1.6) 8,044 (3.0) < 0.001
 Renal complication 90,684 (10.0) 108,959 (40.7) < 0.001
Resource utilization
 Length of stay, mean ± SD (days) 5.3 [1.3, 9.2] 8.5 [2.3, 14.7] < 0.001
 Total cost, mean ± SD (USD) 30,939 ± 52,624 31,426 ± 54,470 0.06
 Total charges, mean ± SD (USD) 81,984 ± 96,368 122,635 ± 192,900 < 0.001

*High-risk comorbidity defined as presence of chronic kidney disease, chronic heart failure, or liver cirrhosis

Values are n (%) unless otherwise indicated