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. 2002 Mar;22(6):1893–1902. doi: 10.1128/MCB.22.6.1893-1902.2002

FIG. 3.

FIG. 3.

Immune complexes are deposited in glomeruli of 21-month-old apoJ/clusterin-deficient mice but not hemizygous mice. Tissue sections from hemizygous (A to C, G to I) and apoJ/clusterin-deficient mice (D to F, J to L) were analyzed with antibodies specific for IgG (A and D), IgM (B and E), IgA (C and F), C1q (G and J), C3 (H and K), and C9 (I and L). Positive staining in a mesangial pattern was seen for the apoJ/clusterin-deficient mice for all markers, with particularly strong accumulation of IgM, IgA, and C9. Magnification, ×360.