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. 2002 Mar;22(6):1893–1902. doi: 10.1128/MCB.22.6.1893-1902.2002

FIG. 6.

FIG. 6.

apoJ/clusterin protects glomeruli from unilateral nephrectomy-accelerated accumulation of immune complex components in the mesangium. Tissue sections from 6-month-old unilaterally nephrectomized wild-type (A to C, G to I) and apoJ/clusterin-deficient mice (D to F, J to L) were analyzed with specific antibodies to IgG (A and D), IgM (B and E), IgA (C and F), C1q (G and J), C3 (H and K), and C9 (I and L). Mesangial pattern staining was detected only in the uninephrectomized apoJ/clusterin-deficient mice. Note also that C9 did not accumulate with either genotype. Magnification, ×400.