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. 2026 Aug 27;15(8):585. doi: 10.21037/tcr-2026-1405

Figure 10.

Figure 10

Role of IL1A expression in the proliferation and invasion of pancreatic cancer cells. (A,B) The transfection of CAPAN-1 and BxPC-3 cells with empty lentivirus (sh-NC) and IL1A knockdown lentivirus (sh-IL1A) was performed, and WB was used to verify the knockdown efficiency of IL1A. (C) The invasion capability of cancer cells was assessed using Transwell assays. Crystal violet staining; 200×. (D,F) The proliferation ability of cancer cells was assessed using CCK-8. (E) The proliferation ability of cancer cells was assessed using colony formation assay. Crystal violet staining; 1× (macroscopic imaging). (H) The expression level of BAX and BCL-2 following IL1A knockdown. (G,I) The degree of apoptosis in the two cancer cells was evaluated through flow cytometry. (J) Western blot for IL1A in PAAD cells treated with polystyrene microspheres. **, P<0.01; ***, P<0.001. CCK-8, Cell Counting Kit-8; PAAD, pancreatic ductal adenocarcinoma.