TABLE 2.
Neuronal counts from Dyrk1A+/+ and Dyrk1A+/− brain regions
| Region | Neuronal counta (mean ± SD)
|
Pb | |
|---|---|---|---|
| Dyrk1A+/+ | Dyrk1A+/− | ||
| Cortical layers II-III | 200.5 ± 11.6 | 262.8 ± 34.5 | < 0.0005 |
| Cortical layer IV | 243.7 ± 34.5 | 312.2 ± 66.4 | 0.015 |
| Cortical layer V | 114.8 ± 14.5 | 152.4 ± 11.6 | < 0.0005 |
| Thalamic VMP | 133.3 ± 16.2 | 153.7 ± 8.3 | 0.03 |
| SC | |||
| SGS | 268.5 ± 20.7 | 277.1 ± 24.3 | 0.46 |
| SO | 223.3 ± 45.9 | 252.3 ± 23.7 | 0.20 |
a
Mean number of neurons per 106 μm2 from four to eight different visual fields (50 μm thick) for each group.
b
By Student's t test.