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SHIRPA primary behavioral assessment of adult Dyrk1A+/− mice
| Testa | Score (mean)
|
Significanceb | |
|---|---|---|---|
| Dyrk1A+/+ | Dyrk1A+/− | ||
| Body position | 3.2 | 3.0 | NS |
| Spontaneous activity | 1.8 | 1.7 | NS |
| Negative geotaxis | 0.4 | 0.6 | NS |
| Toe pinch | 2.1 | 1.9 | NS |
| Corneal reflex | 1.5 | 2.1 | NS |
| Visual placing | 2.6 | 2.4 | NS |
| Fear | 1.0 | 1.0 | NS |
| Irritability | 0.8 | 0.6 | NS |
| Freezing | 1.3 | 1.8 | P = 0.05 |
| Startle response | 3.0 | 2.4 | P = 0.03 |
Only tests relevant to the model are shown.
By Student's t test. NS, not significant.
