| ABMIL | Attention-based multiple-instance learning |
| AI | Artificial intelligence |
| aMIL | Additive multiple-instance learning |
| apCAF | Antigen-presenting cancer-associated fibroblast |
| AQP4 | Aquaporin 4 |
| AUC | Area under the curve |
| CAF | Cancer-associated fibroblast |
| CAF-S1 | Cancer-associated fibroblast subset 1 |
| CAR-T | Chimeric antigen receptor T cell |
| CD4 | Cluster of differentiation 4 |
| CD8 | Cluster of differentiation 8 |
| CD74 | Cluster of differentiation 74 |
| CNN | Convolutional neural network |
| COL5A1 | Collagen type V alpha 1 chain |
| COL11A1 | Collagen type XI alpha 1 chain |
| CTLA-4 | Cytotoxic T-lymphocyte-associated protein 4 |
| CXCL9 | C-X-C motif chemokine ligand 9 |
| CXCL10 | C-X-C motif chemokine ligand 10 |
| CXCL12 | C-X-C motif chemokine ligand 12 |
| CXCR4 | C-X-C motif chemokine receptor 4 |
| DINOv2 | Self-supervised vision transformer model |
| DPP4 | Dipeptidyl peptidase 4 |
| ECM | Extracellular matrix |
| FDA | Food and Drug Administration |
| FAP | Fibroblast activation protein |
| FBLN1 | Fibulin 1 |
| GPU | Graphics processing unit |
| H&E | Hematoxylin and eosin |
| HCC | Hepatocellular carcinoma |
| HE2RNA | H&E-to-RNA prediction model |
| HEST | Histology and spatial transcriptomics |
| HRD | Homologous recombination deficiency |
| ICB | Immune checkpoint blockade |
| IF | Immunofluorescence |
| IL-1 | Interleukin-1 |
| IL-2 | Interleukin-2 |
| IL-6 | Interleukin-6 |
| IMC | Imaging mass cytometry |
| iCAF | Inflammatory cancer-associated fibroblast |
| JAK/STAT | Janus kinase/signal transducer and activator of transcription |
| LAMP5 | Lysosomal-associated membrane protein family member 5 |
| LLM | Large language model |
| LRRC15 | Leucine-rich repeat containing 15 |
| matCAF | Matrix-producing cancer-associated fibroblast |
| MCAM | Melanoma cell adhesion molecule |
| MDSC | Myeloid-derived suppressor cell |
| MHC-II | Major histocompatibility complex class II |
| MIL | Multiple instance learning |
| mIF | Multiplex immunofluorescence |
| MSI | Microsatellite instability |
| myCAF | Myofibroblastic cancer-associated fibroblast |
| NADPH | Nicotinamide adenine dinucleotide phosphate |
| NF-κB | Nuclear factor kappa B |
| NK | Natural killer |
| NKG2A | Natural killer group 2A |
| NOX1 | NADPH oxidase 1 |
| NOX4 | NADPH oxidase 4 |
| NSCLC | Non-small-cell lung cancer |
| PD-1 | Programmed cell death protein 1 |
| PD-L1 | Programmed death-ligand 1 |
| PDGFR | Platelet-derived growth factor receptor |
| POLE | DNA polymerase epsilon |
| RGS5 | Regulator of G protein signaling 5 |
| SaMD | Software as a medical device |
| SDC1 | Syndecan 1 |
| SPP1 | Secreted phosphoprotein 1 |
| SSL | Self-supervised learning |
| TAM | Tumor-associated macrophage |
| TCGA | The Cancer Genome Atlas |
| TGF-β | Transforming growth factor beta |
| THBS1 | Thrombospondin 1 |
| TIL | Tumor-infiltrating lymphocyte |
| TLS | Tertiary lymphoid structure |
| TMB | Tumor mutational burden |
| TME | Tumor microenvironment |
| Treg | Regulatory T cell |
| TSR | Tumor-stroma ratio |
| vCAF | Vascular cancer-associated fibroblast |
| ViT-B | Vision Transformer Base |
| ViT-L | Vision Transformer Large |
| WSI | Whole-slide image |
| YAP1 | Yes-associated protein 1 |
| α-SMA | Alpha-smooth muscle actin |