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. 2026 Aug 28;18(17):2802. doi: 10.3390/cancers18172802
ABMIL Attention-based multiple-instance learning
AI Artificial intelligence
aMIL Additive multiple-instance learning
apCAF Antigen-presenting cancer-associated fibroblast
AQP4 Aquaporin 4
AUC Area under the curve
CAF Cancer-associated fibroblast
CAF-S1 Cancer-associated fibroblast subset 1
CAR-T Chimeric antigen receptor T cell
CD4 Cluster of differentiation 4
CD8 Cluster of differentiation 8
CD74 Cluster of differentiation 74
CNN Convolutional neural network
COL5A1 Collagen type V alpha 1 chain
COL11A1 Collagen type XI alpha 1 chain
CTLA-4 Cytotoxic T-lymphocyte-associated protein 4
CXCL9 C-X-C motif chemokine ligand 9
CXCL10 C-X-C motif chemokine ligand 10
CXCL12 C-X-C motif chemokine ligand 12
CXCR4 C-X-C motif chemokine receptor 4
DINOv2 Self-supervised vision transformer model
DPP4 Dipeptidyl peptidase 4
ECM Extracellular matrix
FDA Food and Drug Administration
FAP Fibroblast activation protein
FBLN1 Fibulin 1
GPU Graphics processing unit
H&E Hematoxylin and eosin
HCC Hepatocellular carcinoma
HE2RNA H&E-to-RNA prediction model
HEST Histology and spatial transcriptomics
HRD Homologous recombination deficiency
ICB Immune checkpoint blockade
IF Immunofluorescence
IL-1 Interleukin-1
IL-2 Interleukin-2
IL-6 Interleukin-6
IMC Imaging mass cytometry
iCAF Inflammatory cancer-associated fibroblast
JAK/STAT Janus kinase/signal transducer and activator of transcription
LAMP5 Lysosomal-associated membrane protein family member 5
LLM Large language model
LRRC15 Leucine-rich repeat containing 15
matCAF Matrix-producing cancer-associated fibroblast
MCAM Melanoma cell adhesion molecule
MDSC Myeloid-derived suppressor cell
MHC-II Major histocompatibility complex class II
MIL Multiple instance learning
mIF Multiplex immunofluorescence
MSI Microsatellite instability
myCAF Myofibroblastic cancer-associated fibroblast
NADPH Nicotinamide adenine dinucleotide phosphate
NF-κB Nuclear factor kappa B
NK Natural killer
NKG2A Natural killer group 2A
NOX1 NADPH oxidase 1
NOX4 NADPH oxidase 4
NSCLC Non-small-cell lung cancer
PD-1 Programmed cell death protein 1
PD-L1 Programmed death-ligand 1
PDGFR Platelet-derived growth factor receptor
POLE DNA polymerase epsilon
RGS5 Regulator of G protein signaling 5
SaMD Software as a medical device
SDC1 Syndecan 1
SPP1 Secreted phosphoprotein 1
SSL Self-supervised learning
TAM Tumor-associated macrophage
TCGA The Cancer Genome Atlas
TGF-β Transforming growth factor beta
THBS1 Thrombospondin 1
TIL Tumor-infiltrating lymphocyte
TLS Tertiary lymphoid structure
TMB Tumor mutational burden
TME Tumor microenvironment
Treg Regulatory T cell
TSR Tumor-stroma ratio
vCAF Vascular cancer-associated fibroblast
ViT-B Vision Transformer Base
ViT-L Vision Transformer Large
WSI Whole-slide image
YAP1 Yes-associated protein 1
α-SMA Alpha-smooth muscle actin