3′-UTR	3′ untranslated region
7TMD	seven-transmembrane domain
ADC	antibody–drug conjugate
ADGRE5	adhesion G-protein-coupled receptor E5
aGPCR	adhesion G-protein-coupled receptor
AI	artificial intelligence
AKT	protein kinase B
AML	acute myeloid leukemia
A-to-I	adenosine-to-inosine
BBB	blood–brain barrier
BTB	blood–tumor barrier
CALR	calreticulin
CAR	chimeric antigen receptor
CAR-T	chimeric antigen receptor T cell
CAR-Th9	chimeric antigen receptor-engineered T helper type 9 cell
cDC2	conventional type 2 dendritic cell
CNS	central nervous system
CopyKAT	Copy Number Karyotyping of Aneuploid Tumors
CRISPR-Cas9	clustered regularly interspaced short palindromic repeats-CRISPR-associated protein 9
CTC	circulating tumor cell
CTF	C-terminal fragment
CXCR2	C-X-C motif chemokine receptor 2
DC	dendritic cell
DLG1	discs large homolog 1
DOPC	1,2-dioleoyl-sn-glycero-3-phosphocholine
ECL1/ECL2	extracellular loops 1 and 2
EGF	epidermal growth factor
EGF-TM7	epidermal growth factor-seven-transmembrane
EMT	epithelial–mesenchymal transition
ENT	extracellular N terminus
ERK	extracellular signal-regulated kinase
Fc	fragment crystallizable
FLT3-ITD	FMS-like tyrosine kinase 3 internal tandem duplication
G13	heterotrimeric G-protein G13
GAG	glycosaminoglycan
GAIN	GPCR autoproteolysis-inducing domain
GBM	glioblastoma
GEO	Gene Expression Omnibus
GLUT1	glucose transporter 1
GMP	granulocyte–monocyte progenitor
GPCR	G-protein-coupled receptor
GPS	GPCR proteolysis site
Gq	heterotrimeric G-protein Gq
Gs	heterotrimeric G-protein Gs
GSC	glioblastoma stem-like cell
HGG	high-grade glioma
HSC	hematopoietic stem cell
HSPC	hematopoietic stem/progenitor cell
HT1080	human fibrosarcoma cell line
ICT	intracellular C terminus
IHC	immunohistochemistry
IL-8	interleukin-8
IUPHAR	International Union of Basic and Clinical Pharmacology
JAK2	Janus kinase 2
Kgp	lysine-specific gingipain
LDHA	lactate dehydrogenase A
LPA	lysophosphatidic acid
LPAR1	lysophosphatidic acid receptor 1
LSC	leukemia stem cell
M0	unpolarized macrophage
MAPK	mitogen-activated protein kinase
miR-379-5p	microRNA-379-5p
miRNA	microRNA
MMP-9	matrix metalloproteinase-9
mRNA	messenger RNA
mTORC2	mechanistic target of rapamycin complex 2
NK	natural killer
NTF	N-terminal fragment
OMIX	Open Archive for Miscellaneous Data
PA	pilocytic astrocytoma
PBM	PDZ-binding motif
PBMC	peripheral blood mononuclear cell
PDB	Protein Data Bank
PDZ	PSD-95/Dlg/ZO-1
PI3K	phosphoinositide 3-kinase
pTPM	protein-coding transcripts per million
RGD	arginine–glycine–aspartate
RNA	ribonucleic acid
RNA-seq	RNA sequencing
shRNA	short hairpin RNA
siRNA	small interfering RNA
ST6GAL1	β-galactoside α-2,6-sialyltransferase 1
STAT3	signal transducer and activator of transcription 3
TCGA	The Cancer Genome Atlas
THP-1	human monocytic leukemia cell line
THY1	Thy-1 cell-surface antigen
TIA	tethered/intramolecular agonist
TM6/TM7 (TMH6/TMH7)	transmembrane helices 6 and 7