FIG. 4.

Stroma and IL-7 dependence correlated with leukemogenic potential of E2A-HLF/BCL2-transduced B-cell progenitors. Cells were cultured in methylcellulose with or without exogenous IL-7 as indicated at the top. Identities of various transduced cell populations, cell lines, and leukemias are indicated at the left. Cloning efficiencies were determined by examination under light microscopy at day 14. Leukemogenic potentials and latencies in immunocompetent, syngeneic recipients are indicated to the right.