TABLE 1.
Cell line | Phenotype | Genotypea | Growth requirements
|
Syngeneic, nonirradiated recipients
|
||
---|---|---|---|---|---|---|
IL-7 | AC-6.21 stroma | Leukemiab | Latency (wk) | |||
BiEH.3-SD | B220+ CD43+ CD24+ BP1− IgM− | IgHM, IgLG | + | + | − | NAc |
BiEH.4-SD | B220+ CD43+ CD24+ BP1− IgM− | IgHM, IgLG | + | + | − | NA |
BiEH.1-SI | B220+ CD43+ CD24+ BP1− IgM− | IgHR, IgLR | + | − | − | NA |
BiEH.2-SI | B220+ CD43+ CD24+ BP1+ IgM+ | IgHR, IgLR | + | − | − | NA |
BiEH.3-SI | B220+ CD43+ CD24+ BP1− IgM− | IgHR, IgLG | + | − | − | NA |
BiEH.4-SI | B220+ CD43+ CD24+ BP1− IgM− | IgHR, IgLG | + | − | − | NA |
BiEH.5 | B220+ CD43+ CD24+ BP1+ IgMlo | IgHR, IgLR | − | − | + | 3-4 |
p190.1 | B220+ CD43+ CD24+ BP1+ IgM− | IgHR, IgLG | − | − | + | 2-3 |
7iEH-SD | B220+ CD43+ CD24+ BP1+ IgM− | IgHM, IgLG | − | + | − | NA |
7iEH-SI | B220+ CD43+ CD24+ BP1+ IgM− | IgHR, IgLG | − | − | + | 2-3 |
IgHM, multiple immunoglobulin heavy-chain gene rearrangements; IgHR, one or two immunoglobulin heavy-chain gene rearrangements; IgLG, germ line immunoglobulin light-chain gene configuration.
That is, 106 cells injected i.v.
NA, not applicable.