TABLE 2.
Parameter | Result for:
|
|
---|---|---|
Wild-type mice | Calnexin gene knockout mice | |
Visual placing | Normal | Normal |
Startle response | Normal | Normal |
Righting reflex | Normal | Normal |
Sensory system | Normal | Normal |
Tremor | None | Marked |
Gait | Normal | Fluid but abnormal |
Abnormal behavior | None | Retroplusion, negative geotaxis |
Results show that calnexin gene-deficient mice have normal visual and hearing abilities, normal sensory reflexes, and a normal righting reflex but show a clearly unsteady gait, tremor, and abnormal behavior such as retropulsion and negative geotaxis.