| Aβ | amyloid-β |
| AD | Alzheimer’s disease |
| ADP | adenosine diphosphate |
| APOE | apolipoprotein E |
| APP | amyloid precursor protein |
| ARIA | amyloid-related imaging abnormalities |
| AT(N) | amyloid, tau, and neurodegeneration |
| ATP | adenosine triphosphate |
| BACE | β-site amyloid precursor protein-cleaving enzyme |
| BBB | blood–brain barrier |
| CDR-SB | clinical dementia rating-sum of boxes |
| CSF | cerebrospinal fluid |
| Cyt c | cytochrome c |
| DNA | deoxyribonucleic acid |
| EEG | electroencephalography |
| FDG-PET | fluorodeoxyglucose positron emission tomography |
| FINGER | Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability |
| FMT | fecal microbiota transplantation |
| GFAP | glial fibrillary acidic protein |
| GWAS | genome-wide association study |
| LATE | limbic-predominant age-related TDP-43 encephalopathy |
| LDL | low-density lipoprotein |
| MAPT | microtubule-associated protein tau |
| MEG | magnetoencephalography |
| MRI | magnetic resonance imaging |
| NAFLD | non-alcoholic fatty liver disease |
| NfL | neurofilament light |
| NIA–AA | National Institute on Aging–Alzheimer’s Association |
| PET | positron emission tomography |
| PSEN | presenilin |
| p-tau | phosphorylated tau |
| RNA | ribonucleic acid |
| ROS | reactive oxygen species |
| SASP | senescence-associated secretory phenotype |
| SCFAs | short-chain fatty acids |
| TCA | tricarboxylic acid |
| TDP-43 | transactive response DNA-binding protein 43 kDa |
| TREM2 | triggering receptor expressed on myeloid cells 2 |
| Ub | ubiquitin |