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. 2026 Aug 28;15(17):1563. doi: 10.3390/cells15171563
AKI acute kidney injury
ATP adenosine triphosphate
CCL14 C-C motif chemokine ligand 14
CKD chronic kidney disease
CTLA-4 cytotoxic T-lymphocyte-associated protein 4
DNA deoxyribonucleic acid
eGFR estimated glomerular filtration rate
FR-PTCs failed-repair proximal tubular cells
ICI immune checkpoint inhibitor
IL-18 interleukin-18
KIM-1 kidney injury molecule-1
L-FABP liver-type fatty acid-binding protein
NGAL neutrophil gelatinase-associated lipocalin
PD-1 programmed cell death protein 1
PD-L1 programmed death-ligand 1
PGC-1α peroxisome proliferator-activated receptor-γ coactivator-1α
RNA ribonucleic acid
SIRT1 sirtuin 1
SOX9 SRY-box transcription factor 9
TIMP-2 tissue inhibitor of metalloproteinases-2
IGFBP7 insulin-like growth factor-binding protein 7
TIMP-2·IGFBP7 tissue inhibitor of metalloproteinases-2 and insulin-like growth factor-binding protein 7
TMA thrombotic microangiopathy
uEVs urinary extracellular vesicles
VEGF vascular endothelial growth factor
Wnt Wingless/Integrated signaling pathway
YAP Yes-associated protein