ADL	Activities of Daily Living
AE	Adverse event
AS	Active surveillance
CARG	Cancer and Aging Research Group
ccRCC	Clear-cell renal cell carcinoma
CFS	Clinical Frailty Scale
CGA	Comprehensive Geriatric Assessment
CIRS-G	Cumulative Illness Rating Scale—Geriatrics
ctDNA	Circulating tumor DNA
DISSRM	Delayed Intervention and Surveillance for Small Renal Masses
ECOG	Eastern Cooperative Oncology Group
EORTC	European Organisation for Research and Treatment of Cancer
G8	Geriatric 8 screening tool
GDS-15	15-item Geriatric Depression Scale
HIF-2α	Hypoxia-inducible factor 2 alpha
IADL	Instrumental Activities of Daily Living
ICI	Immune checkpoint inhibitor
irAE	Immune-related adverse event
KIM-1	Kidney injury molecule-1
KPS	Karnofsky Performance Status
MeSHs	Medical Subject Headings
MNA	Mini Nutritional Assessment
MNA-SF	Mini Nutritional Assessment—Short Form
MoCA	Montreal Cognitive Assessment
mTOR	Mammalian target of rapamycin
OCEBM	Oxford Centre for Evidence-Based Medicine
ORR	Objective response rate
OS	Overall survival
PD-1	Programmed death-1
PD-L1	Programmed death-ligand 1
PFS	Progression-free survival
PROM	Patient-reported outcome measure
QoL	Quality of life
SBRT	Stereotactic body radiotherapy
SII	Systemic immune–inflammation index
TKI	Tyrosine kinase inhibitor
TrAE	Treatment-related adverse event
VEGF	Vascular endothelial growth factor
VEGFR	Vascular endothelial growth factor receptor