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. 2026 Sep 6;27(17):7937. doi: 10.3390/ijms27177937
AChE acetylcholinesterase
AE anion exchanger
AKT protein kinase B
ATM ataxia-telangiectasia mutated kinase
Bax Bcl-2-associated X protein
Bcl-2 B-cell lymphoma 2
BuChE butyrylcholinesterase
CAF cancer-associated fibroblast
CAGE Calcium-Gated Excitability
CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha-2/delta-1 gene
Cav voltage-gated calcium channel
CCL4 C–C motif chemokine ligand 4
CCL5 C–C motif chemokine ligand 5
CD8 cluster of differentiation 8
ChAT choline acetyltransferase
CHRFAM7A CHRNA7 family with sequence similarity 7A gene
CHRNA4 cholinergic receptor nicotinic alpha 4 subunit gene
CHRNA7 cholinergic receptor nicotinic alpha 7 subunit gene
CHRNB2 cholinergic receptor nicotinic beta 2 subunit gene
CICR calcium-induced calcium release
CNS central nervous system
CRAC calcium release-activated calcium
CRC colorectal cancer
CSC cancer stem cell
cAMP cyclic adenosine monophosphate
DHβE dihydro-β-erythroidine
ECM extracellular matrix
EC50 half-maximal effective concentration
EGFR chloride equilibrium potential
ECl epidermal growth factor receptor
EMT epithelial–mesenchymal transition
ER endoplasmic reticulum
ERK extracellular signal-regulated kinase
GABA γ-aminobutyric acid
GABAA γ-aminobutyric acid type A receptor
GABAB γ-aminobutyric acid type B receptor
GABBR1 gamma-aminobutyric acid type B receptor subunit 1 gene
GAD1 glutamate decarboxylase 1 gene
GAD65 65 kDa glutamate decarboxylase isoform
GENI genetically encoded neurotransmitter indicator
Gi/o inhibitory G-protein family
Gαi/o inhibitory G-protein alpha subunit
Gαq G-protein alpha q subunit
Gβγ G-protein beta-gamma subunit complex
GSK-3β glycogen synthase kinase-3 beta
HCC hepatocellular carcinoma
HIF-1α hypoxia-inducible factor 1 alpha
HUVEC human umbilical vein endothelial cell
IC50 half-maximal inhibitory concentration
IFP interstitial fluid pressure
IHC immunohistochemistry
IL-10 interleukin 10
IP3 inositol 1,4,5-trisphosphate
IP3R inositol 1,4,5-trisphosphate receptor
JAK Janus kinase
KCC1 K+–Cl− cotransporter 1
KCC2 K+–Cl− cotransporter 2
KCC3 K+–Cl− cotransporter 3
Ly6/uPAR lymphocyte antigen 6/urokinase-type plasminogen activator receptor
MAPK mitogen-activated protein kinase
MERFISH multiplexed error-robust fluorescence in situ hybridization
mTORC2 mechanistic target of rapamycin complex 2
nAChR nicotinic acetylcholine receptor
NBC sodium–bicarbonate cotransporter
NF-κB nuclear factor kappa B
NKCC1 Na+–K+–2Cl− cotransporter 1
NNK 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
NSCLC non-small cell lung cancer
PI3K phosphoinositide 3-kinase
PLC phospholipase C
PKA protein kinase A
SLC12A2 solute carrier family 12 member 2 gene
SLC12A5 solute carrier family 12 member 5 gene
SLURP-1 secreted Ly6/uPAR-related protein 1
SOCE store-operated calcium entry
STAT signal transducer and activator of transcription
STIM stromal interaction molecule
TAM tumor-associated macrophage
TIF tumor interstitial fluid
TME tumor microenvironment
TNBC triple-negative breast cancer
TRP transient receptor potential
VAChT vesicular acetylcholine transporter
VGCC voltage-gated calcium channel
γH2AX phosphorylated histone H2AX