Figure 7.

eEF1A-1 and markers of oxidative and ER stress are increased in lipotoxic cardiac tissue. (A) Representative immunoblotting of eEF1A-1, catalase, ER chaperone proteins (GRP78 and PDI), and actin in whole tissue homogenates from ventricles of 12-wk-old wild-type or MHC-ACS mice. Blots are representative of the four animals included in each group. Open arrow indicates nonspecific protein bands. (B) Densitometry of immunoblotting, as shown in A. Data expressed as mean of the protein to actin ratio ± SEM for four animals in each group, ^*p < 0.05.