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. 2026 Sep 2;27(17):7863. doi: 10.3390/ijms27177863
1,25(OH)2D3 1,25-dihydroxyvitamin D3 (calcitriol)
2-HG 2-hydroxyglutarate
25(OH)D 25-hydroxyvitamin D
5hmC 5-hydroxymethylcytosine
5mC 5-methylcytosine
ABC ATP-binding cassette
ACE angiotensin-converting enzyme
AKT protein kinase B
ALL acute lymphoblastic leukemia
ALOX5 arachidonate 5-lipoxygenase
α-KG alpha-ketoglutarate
ALT alanine aminotransferase
AMPK AMP-activated protein kinase
Apaf-1 apoptotic protease-activating factor 1
ARE antioxidant response element
ASC apoptosis-associated speck-like protein containing a CARD
ACMSD α-amino-β-carboxy-muconate-semialdehyde decarboxylase
AST aspartate aminotransferase
ATG5 autophagy-related protein 5
ATM ataxia–telangiectasia mutated
ATP adenosine triphosphate
BAK BCL-2 antagonist/killer 1
BAX BCL-2-associated X protein
BCL-2 B-cell lymphoma 2
Bcl-xL B-cell lymphoma-extra large
BCRP breast cancer resistance protein
Bmi-1 BMI1 proto-oncogene, polycomb ring finger
BNP B-type natriuretic peptide
BTG2 B-cell translocation gene 2
CARD caspase activation and recruitment domain
CCSS Childhood Cancer Survivor Study
CDK1 cyclin-dependent kinase 1
CGI(s) CpG island(s)
CHKB-DT choline kinase beta divergent transcript
circRNA(s) circular RNA(s)
CK creatine kinase
CK-MB creatine kinase-MB isoenzyme
CoA coenzyme A
CoQ10 coenzyme Q10
CpG cytosine–phosphate–guanine dinucleotide
CpH non-CpG cytosine context in which H denotes A, C, or T
cTnT cardiac troponin T
Cyt c cytochrome c
DHA docosahexaenoic acid
DLBCL diffuse large B-cell lymphoma
DMS differentially methylated sites
DNA deoxyribonucleic acid
DNMT(s) DNA methyltransferase(s)
DNMT1 DNA methyltransferase 1
DNMT3A DNA methyltransferase 3 alpha
DNMT3B DNA methyltransferase 3 beta
DOX doxorubicin
Drp1 dynamin-related protein 1
EDTA ethylenediaminetetraacetic acid
EGCG epigallocatechin-3-gallate
EGFR epidermal growth factor receptor
EndMT endothelial-to-mesenchymal transition
EPA eicosapentaenoic acid
ERK1/2 extracellular signal-regulated kinases 1 and 2
ETC electron transport chain
ETS electron transport system
Fas Fas cell surface death receptor
FasL Fas ligand
FDA US Food and Drug Administration
Fis1 mitochondrial fission protein 1
FMT fecal microbiota transplantation
Fn14 fibroblast growth factor-inducible 14
γH2AX phosphorylated histone H2AX
GCLC glutamate–cysteine ligase catalytic subunit
GCLM glutamate–cysteine ligase modifier subunit
GLS global longitudinal strain
GPx glutathione peroxidase
GPX4 glutathione peroxidase 4
GSDMD gasdermin D
GSH glutathione
H2AK119Ub monoubiquitination of histone H2A at lysine 119
H2AX histone H2A variant X
H3K27ac acetylation of histone H3 lysine 27
H3K27me3 trimethylation of histone H3 lysine 27
H3K4 histone H3 lysine 4
H3K4me1 monomethylation of histone H3 lysine 4
H3K4me3 trimethylation of histone H3 lysine 4
H9c2 rat embryonic cardiomyoblast cell line
HAT(s) histone acetyltransferase(s)
HAX-1 HCLS1-associated protein X-1
HCM-ls human cardiomyocyte-like cells
HDAC(s) histone deacetylase(s)
HDM(s) histone demethylase(s)
HER2 human epidermal growth factor receptor 2
HF heart failure
HINT2 histidine triad nucleotide-binding protein 2
HM(s) histone modification(s)
HMT(s) histone methyltransferase(s)
HO-1 heme oxygenase-1
HUVEC(s) human umbilical vein endothelial cell(s)
ICAM-1 intercellular adhesion molecule-1
IDH isocitrate dehydrogenase(s)
IDO1 indoleamine 2,3-dioxygenase 1
IGF-1 insulin-like growth factor 1
IL interleukin
iNOS inducible nitric oxide synthase
JMJD3 Jumonji domain-containing protein 3
JNK c-Jun N-terminal kinase
Keap1 Kelch-like ECH-associated protein 1
LC3I/II microtubule-associated protein 1 light chain 3 I/II
LDH lactate dehydrogenase
LGE late gadolinium enhancement
lncRNA(s) long non-coding RNA(s)
LPS lipopolysaccharide
LVEF left ventricular ejection fraction
MAPK(s) mitogen-activated protein kinase(s)
MCM-41 Mobil Composition of Matter No. 41
MCP-1 monocyte chemoattractant protein-1
mCpH methylated CpH
MDA malondialdehyde
MeCP2 methyl-CpG-binding protein 2
Mfn2 mitofusin 2
miR/miRNA(s) microRNA(s)
MitoQ mitoquinone
MnSOD manganese superoxide dismutase
mPTP mitochondrial permeability transition pore
MRI magnetic resonance imaging
mRNA(s) messenger RNA(s)
MRP1 multidrug resistance-associated protein 1
mtDNA mitochondrial DNA
mTOR mechanistic target of rapamycin
mTORC1 mechanistic target of rapamycin complex 1
NAC N-acetylcysteine
NAD+ nicotinamide adenine dinucleotide
NADPH reduced nicotinamide adenine dinucleotide phosphate
ncRNA(s) non-coding RNA(s)
NF-κB nuclear factor kappa B
NLRP3 NLR family pyrin domain-containing 3
NO nitric oxide
NORAD non-coding RNA activated by DNA damage
NOX4 NADPH oxidase 4
NQO1 NAD(P)H quinone oxidoreductase 1
NRF1/2 nuclear respiratory factors 1 and 2
Nrf2 nuclear factor erythroid 2-related factor 2
NT-proBNP N-terminal pro-B-type natriuretic peptide
OPA1 optic atrophy 1
OS oxidative stress
p21 cyclin-dependent kinase inhibitor 1A
p53 tumor protein p53
PAGln phenylacetylglutamine
PGC-1α peroxisome proliferator-activated receptor gamma coactivator 1-alpha
PI3K phosphoinositide 3-kinase
PINK1 PTEN-induced kinase 1
piRNA(s) PIWI-interacting RNA(s)
PTM(s) post-translational modification(s)
PTPN2 protein tyrosine phosphatase non-receptor type 2
PUFA(s) polyunsaturated fatty acid(s)
QPRT quinolinate phosphoribosyltransferase
Rac1 Ras-related C3 botulinum toxin substrate 1
Res-SLN resveratrol-loaded solid lipid nanoparticles
RNA ribonucleic acid
RNS reactive nitrogen species
ROS reactive oxygen species
rRNA(s) ribosomal RNA(s)
SAM S-adenosylmethionine
SCFA(s) short-chain fatty acid(s)
Se@CM selenium-enriched Cordyceps militaris-based oral microcarrier
SERCA sarco/endoplasmic reticulum Ca2+-ATPase
SESN2 sestrin 2
SGK1 serum/glucocorticoid-regulated kinase 1
siRNA(s) small interfering RNA(s)
SIRT(s) sirtuin(s)
SJLIFE St. Jude Lifetime Cohort Study
SKQ1 mitochondria-targeted plastoquinone derivative
sncRNA(s) small non-coding RNA(s)
snoRNA(s) small nucleolar RNA(s)
snRNA(s) small nuclear RNA(s)
SOD superoxide dismutase
STAT signal transducer and activator of transcription
TET(s) ten-eleven translocation enzyme(s)
TET1 ten-eleven translocation methylcytosine dioxygenase 1
TET2 ten-eleven translocation methylcytosine dioxygenase 2
TET3 ten-eleven translocation methylcytosine dioxygenase 3
TF(s) transcription factor(s)
TFAM mitochondrial transcription factor A
TFEB transcription factor EB
TGF-β transforming growth factor beta
TINCR terminal differentiation-induced non-coding RNA
TNF-α tumor necrosis factor alpha
TOP2α topoisomerase II alpha
TOP2β topoisomerase II beta
TPGS D-α-tocopheryl polyethylene glycol 1000 succinate
tRNA(s) transfer RNA(s)
TUNEL terminal deoxynucleotidyl transferase dUTP nick-end labeling
TWEAK TNF-like weak inducer of apoptosis
TXNRD thioredoxin reductase
VC/VK3 ascorbate and menadione sodium bisulfite
VCAM-1 vascular cell adhesion molecule-1
VDR vitamin D receptor
Xc− cystine/glutamate antiporter system Xc−
YAP Yes-associated protein
ZO-1 zonula occludens-1