TABLE 2.
Summary of anti-brecPrP MAbs specific for linear epitopes of protease K-resistant sheep PrPSc
| MAb | Isotype | Mouse strain | Epitopea |
|---|---|---|---|
| M2182 | IgG1 | BALB/c | HVAGAAAAGAVVG (aa 122-134) |
| M2197 | IgG1 | BALB/c | |
| M2200 | IgG1 | BALB/c | |
| M2281 | IgG2a | NZB/NZW F1 | |
| M2188 | IgG2b | BALB/c | SRPLIHFG (aa 146-153) |
| M2199 | IgG1 | BALB/c | KMMERVVEQMCITQY (aa 215-229) |
| M2283 | IgG2b | NZB/NZW F1 | GENFTETDI (aa 206-214) |
Position numbers represent the bovine amino acid sequence.