| AFP | alpha-fetoprotein |
| AgFON | silver film over nanospheres |
| AI | artificial intelligence |
| ALN | alendronate |
| ANNs | artificial neural networks |
| APTES | (3-Aminopropyl)triethoxysilane |
| APTMS | (3-Aminopropyl)trimethoxysilane |
| ASOs | antisense oligonucleotides |
| ATP | adenosine triphosphate |
| AuNS | gold nanostars |
| BBB | blood–brain barrier |
| BPNPs | biodegradable polymeric NPs |
| CARPA | complement activation-related pseudoallergy |
| CCR2 | C-C Chemokine Receptor Type 2 |
| CD | Cluster of Differentiation |
| CDK | Cyclin-Dependent Kinase |
| CEA | Carcinoembryonic Antigen |
| cGAS | Cyclic GMP-AMP Synthase |
| CH | chitosan |
| CMC | Chemistry, Manufacturing, and Controls |
| CNNs | convolutional neural networks |
| CPPs | critical process parameters |
| CTC | circulating tumor cells |
| CUR | curcumin |
| CXCR4 | C-X-C Chemokine Receptor Type 4 |
| DLS | Dynamic Light Scattering |
| DNA | deoxyribonucleic acid |
| DNN(s) | deep neural network(s) |
| DOX | doxorubicin |
| DPPH | 2,2-Diphenyl-1-picrylhydrazyl |
| ECM | extracellular matrix |
| EGCG | epigallocatechin gallate |
| EGFR | Epidermal Growth Factor Receptor |
| EGFRvIII | Epidermal Growth Factor Receptor Variant III |
| EMA | European Medicines Agency |
| EpCAM | Epithelial Cell Adhesion Molecule |
| EPR | enhanced permeability and retention |
| ErbB2 | Erythroblastic Oncogene B2 (HER2) |
| EVs | extracellular vesicles |
| FA | folic acid |
| FDA | Food and Drug Administration |
| FUS | focused ultrasound |
| GANs | generative adversarial networks |
| GLUT | Glucose Transporter |
| GMP | Good Manufacturing Practice |
| GNNs | graph neural networks |
| GNRs | gold nanorods |
| GSH | glutathione |
| HA | hyaluronic acid |
| HAase | hyaluronidase |
| HAp | hydroxyapatite |
| HCQ | hydroxychloroquine |
| HCS | High-Content Screening |
| HER2 | Human Epidermal Growth Factor Receptor 2 |
| HIF | Hypoxia-Inducible Factor |
| HPH | high-pressure homogenization |
| HSA | human serum albumin |
| HSP70 | Heat Shock Protein 70 |
| HTS | High-Throughput Screening |
| HUVEC | Human Umbilical Vein Endothelial Cell |
| HYAL1/HYAL2 | hyaluronidase 1/2 |
| IC50 | half-maximal inhibitory concentration |
| ICD | immunogenic cell death |
| IDO | indoleamine 2,3-dioxygenase |
| IFP | interstitial fluid pressure |
| IL-10 | interleukin-10 |
| IRF3 | Interferon Regulatory Factor 3 |
| IVIS | in vivo imaging system |
| KRAS | Kirsten Rat Sarcoma Viral Oncogene Homolog |
| LBNPs | lipid-based NPs |
| LCA | Life Cycle Assessment |
| LNP(s) | lipid nanoparticle(s) |
| LSPR | localized surface plasmon resonance |
| LYC | lycopene |
| MAPK | mitogen-activated protein kinase |
| MCTSs | multicellular tumor spheroids |
| MD | molecular dynamics |
| MDR | multidrug resistance |
| MIRIBEL | Minimum Information Reporting in Bio–Nano Experimental Literature |
| MISEV2023 | Minimal Information for Studies of Extracellular Vesicles 2023 |
| miRNA | microRNA |
| ML | Machine Learning |
| MMP | matrix metalloproteinase |
| MOF(s) | metal–organic framework(s) |
| MPS | mononuclear phagocyte system |
| mRNA | messenger RNA |
| MRI | Magnetic Resonance Imaging |
| MS | Mass Spectrometry |
| MSNs | mesoporous silica NPs |
| NF-κB | Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells |
| NLCs | nanostructured lipid carriers |
| NIR | near-infrared |
| NKT | Natural Killer T (cell) |
| NPs | NPs |
| OoC | organ-on-a-chip |
| PA | photoacoustic |
| PAT | process analytical technologies |
| PBPK | physiologically-based pharmacokinetic |
| PCL | polycaprolactone |
| PD-1 | Programmed Cell Death Protein 1 |
| PD-L1 | Programmed Death-Ligand 1 |
| PDA | polydopamine |
| PDOs | patient-derived organoids |
| PDT | photodynamic therapy |
| PDX | Patient-Derived Xenograft |
| PEG | Polyethylene Glycol |
| P-gp | P-glycoprotein |
| PHEA | α,β-Poly(N-2-hydroxyethyl)-D,L-aspartamide |
| PI | propidium iodide |
| PLA | polylactic acid |
| PLGA | poly(lactic-co-glycolic acid) |
| PNIPAM | poly(N-isopropylacrylamide) |
| PTT | photothermal therapy |
| PVA | poly(vinyl alcohol) |
| PVP | polyvinylpyrrolidone |
| QbD | Quality by Design |
| QSAR | quantitative structure–activity relationship |
| RAFT | Reversible Addition–Fragmentation Chain Transfer |
| RBC | red blood cell (erythrocyte) |
| RGD | arginine-glycine-aspartate (peptide) |
| RHE | reconstructed human epidermis |
| RISC | RNA-Induced Silencing Complex |
| RNA | ribonucleic acid |
| ROS | reactive oxygen species |
| SbD | Safe-by-Design |
| SDL | self-driving laboratory |
| SEM | scanning electron microscopy |
| SERS | Surface-Enhanced Raman Spectroscopy/Scattering |
| SEDDS | Self-Emulsifying Drug Delivery Systems |
| SHAP | SHapley Additive exPlanations |
| siRNA | small interfering RNA |
| SIRPα | Signal Regulatory Protein Alpha |
| SLNs | solid lipid NPs |
| SORT | selective organ targeting |
| SPION(s) | superparamagnetic iron oxide nanoparticle(s) |
| STING | Stimulator of Interferon Genes |
| SWCNTs | single-walled carbon nanotubes |
| TAMs | tumor-associated macrophages |
| TBK1 | TANK-Binding Kinase 1 |
| TEM | transmission electron microscopy |
| TEXs | tumor-derived exosomes |
| TGF-β | Transforming Growth Factor Beta |
| THY | thymol |
| TLR | Toll-Like Receptor |
| TME | tumor microenvironment |
| TNBC | triple-negative breast cancer |
| TPP | Target Product Profile |
| UCNPs | upconversion NPs |
| UV | ultraviolet |
| VAEs | variational autoencoders |
| VEGF | Vascular Endothelial Growth Factor |
| WBC | white blood cell |
| XAI | explainable artificial intelligence |
| XGBoost | Extreme Gradient Boosting |
| ZIF-8 | Zeolitic Imidazolate Framework-8 |