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. 2026 Sep 1;19(17):3729. doi: 10.3390/ma19173729
AFP alpha-fetoprotein
AgFON silver film over nanospheres
AI artificial intelligence
ALN alendronate
ANNs artificial neural networks
APTES (3-Aminopropyl)triethoxysilane
APTMS (3-Aminopropyl)trimethoxysilane
ASOs antisense oligonucleotides
ATP adenosine triphosphate
AuNS gold nanostars
BBB blood–brain barrier
BPNPs biodegradable polymeric NPs
CARPA complement activation-related pseudoallergy
CCR2 C-C Chemokine Receptor Type 2
CD Cluster of Differentiation
CDK Cyclin-Dependent Kinase
CEA Carcinoembryonic Antigen
cGAS Cyclic GMP-AMP Synthase
CH chitosan
CMC Chemistry, Manufacturing, and Controls
CNNs convolutional neural networks
CPPs critical process parameters
CTC circulating tumor cells
CUR curcumin
CXCR4 C-X-C Chemokine Receptor Type 4
DLS Dynamic Light Scattering
DNA deoxyribonucleic acid
DNN(s) deep neural network(s)
DOX doxorubicin
DPPH 2,2-Diphenyl-1-picrylhydrazyl
ECM extracellular matrix
EGCG epigallocatechin gallate
EGFR Epidermal Growth Factor Receptor
EGFRvIII Epidermal Growth Factor Receptor Variant III
EMA European Medicines Agency
EpCAM Epithelial Cell Adhesion Molecule
EPR enhanced permeability and retention
ErbB2 Erythroblastic Oncogene B2 (HER2)
EVs extracellular vesicles
FA folic acid
FDA Food and Drug Administration
FUS focused ultrasound
GANs generative adversarial networks
GLUT Glucose Transporter
GMP Good Manufacturing Practice
GNNs graph neural networks
GNRs gold nanorods
GSH glutathione
HA hyaluronic acid
HAase hyaluronidase
HAp hydroxyapatite
HCQ hydroxychloroquine
HCS High-Content Screening
HER2 Human Epidermal Growth Factor Receptor 2
HIF Hypoxia-Inducible Factor
HPH high-pressure homogenization
HSA human serum albumin
HSP70 Heat Shock Protein 70
HTS High-Throughput Screening
HUVEC Human Umbilical Vein Endothelial Cell
HYAL1/HYAL2 hyaluronidase 1/2
IC50 half-maximal inhibitory concentration
ICD immunogenic cell death
IDO indoleamine 2,3-dioxygenase
IFP interstitial fluid pressure
IL-10 interleukin-10
IRF3 Interferon Regulatory Factor 3
IVIS in vivo imaging system
KRAS Kirsten Rat Sarcoma Viral Oncogene Homolog
LBNPs lipid-based NPs
LCA Life Cycle Assessment
LNP(s) lipid nanoparticle(s)
LSPR localized surface plasmon resonance
LYC lycopene
MAPK mitogen-activated protein kinase
MCTSs multicellular tumor spheroids
MD molecular dynamics
MDR multidrug resistance
MIRIBEL Minimum Information Reporting in Bio–Nano Experimental Literature
MISEV2023 Minimal Information for Studies of Extracellular Vesicles 2023
miRNA microRNA
ML Machine Learning
MMP matrix metalloproteinase
MOF(s) metal–organic framework(s)
MPS mononuclear phagocyte system
mRNA messenger RNA
MRI Magnetic Resonance Imaging
MS Mass Spectrometry
MSNs mesoporous silica NPs
NF-κB Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells
NLCs nanostructured lipid carriers
NIR near-infrared
NKT Natural Killer T (cell)
NPs NPs
OoC organ-on-a-chip
PA photoacoustic
PAT process analytical technologies
PBPK physiologically-based pharmacokinetic
PCL polycaprolactone
PD-1 Programmed Cell Death Protein 1
PD-L1 Programmed Death-Ligand 1
PDA polydopamine
PDOs patient-derived organoids
PDT photodynamic therapy
PDX Patient-Derived Xenograft
PEG Polyethylene Glycol
P-gp P-glycoprotein
PHEA α,β-Poly(N-2-hydroxyethyl)-D,L-aspartamide
PI propidium iodide
PLA polylactic acid
PLGA poly(lactic-co-glycolic acid)
PNIPAM poly(N-isopropylacrylamide)
PTT photothermal therapy
PVA poly(vinyl alcohol)
PVP polyvinylpyrrolidone
QbD Quality by Design
QSAR quantitative structure–activity relationship
RAFT Reversible Addition–Fragmentation Chain Transfer
RBC red blood cell (erythrocyte)
RGD arginine-glycine-aspartate (peptide)
RHE reconstructed human epidermis
RISC RNA-Induced Silencing Complex
RNA ribonucleic acid
ROS reactive oxygen species
SbD Safe-by-Design
SDL self-driving laboratory
SEM scanning electron microscopy
SERS Surface-Enhanced Raman Spectroscopy/Scattering
SEDDS Self-Emulsifying Drug Delivery Systems
SHAP SHapley Additive exPlanations
siRNA small interfering RNA
SIRPα Signal Regulatory Protein Alpha
SLNs solid lipid NPs
SORT selective organ targeting
SPION(s) superparamagnetic iron oxide nanoparticle(s)
STING Stimulator of Interferon Genes
SWCNTs single-walled carbon nanotubes
TAMs tumor-associated macrophages
TBK1 TANK-Binding Kinase 1
TEM transmission electron microscopy
TEXs tumor-derived exosomes
TGF-β Transforming Growth Factor Beta
THY thymol
TLR Toll-Like Receptor
TME tumor microenvironment
TNBC triple-negative breast cancer
TPP Target Product Profile
UCNPs upconversion NPs
UV ultraviolet
VAEs variational autoencoders
VEGF Vascular Endothelial Growth Factor
WBC white blood cell
XAI explainable artificial intelligence
XGBoost Extreme Gradient Boosting
ZIF-8 Zeolitic Imidazolate Framework-8