FIG. 6.

Ocular examination. (a) Electroretinograms of 2 Ctns^−/− mice and a control C57BL/6 mouse. The Ctns^−/− mouse A presents a supernormal ERG, the amplitude is increased for the scotopic and photopic responses. For the Ctns^−/− mouse B, the amplitude is severely impaired for both responses. (b) Slit lamp photography of the cornea of a Ctns^−/− mouse. Cystine crystals, consisting of fine white, needle-shaped points, can be observed in the cornea. (c) Funduscopic photography of the retina of a Ctns^−/− mouse. Patches of depigmentation are seen in the peripheral retina.