Subject	Neuroscience; Experimental Surgery
Specific subject area	Stereotaxic surgery; Epilepsy animal models; Corpus callosotomy; Surgical protocols
Type of data	Protocol description; Figures; Tables
How data were acquired	Stereotaxic surgical procedures in adult Wistar rats; PTZ kindling and behavioral observation; Video recording
Data format	Step-by-step protocol with stereotaxic coordinates, anesthesia doses, and behavioral classification criteria
Parameters for data collection	Adult male Wistar rats (500–700 g; 8–9 months); PTZ 37.5 mg/kg i.p.; Paxinos & Watson atlas; Revised Racine scale
Description of data collection	Animals underwent PTZ kindling (7 sessions) followed by stereotaxic callosotomy (PC or TC) and postoperative PTZ rechallenge at day 7
Data source location	Institution: PUC-SP — Faculdade de Ciências Médicas e da Saúde City/Town/Region: Sorocaba, São Paulo Country: Brazil
Data accessibility	The raw data underlying this protocol comprise: (i) video recordings of all PTZ kindling and postoperative rechallenge sessions; (ii) per-animal Racine-grade scoring sheets (duration of each seizure grade per session); (iii) surgical-duration logs; (iv) body-weight records (day of surgery and day of rechallenge); (v) postoperative pain-monitoring sheets; and (vi) the statistical analysis output (R). These files are not currently deposited in a public repository; they are retained by the corresponding author for at least 5 years following publication and are available on reasonable request.
Related research article	Cavalcanti VB et al. Comparative effects of posterior versus total corpus callosotomy in a PTZ-induced rat model of epilepsy: a methodological pilot study. Experimental Brain Research 2026, doi:10.1007/s00221-026-07375-x.