TABLE 2.

Zosteriform challenge of mice immunized with SSIEFARL loaded chaperones

Immunogen	Challenge (HSV-1 = 5 LD50)a at:
	Acute phase			Memory phase
	Mortalityb	Severityc	DDd	Mortalityd	Severityd	DD
SSIEFARL	100	5	8	ND
rhsp70-peptide	0	2.6	80	4.5f	12
VvgB	2.5	2.5	15	53	3.1	14
UV-inactivated HSV	0	<1	0	1.5
rshp70	100	5	9	ND
BSA-peptide	100	5	ND

^aIntracutaneous challenge with 5 LD₅₀s of HSV-1 strain-17. Acute phase, 7 days postimmunization; memory phase, 90 days postimmunization. DD, average day of death.

^bAverage of two separate experiments involving 12 mice per group.

^cZL severity as measured at day 10 postchallenge.

^dAverage of two experiments involving 20 mice per group. ND, not done.

^eZL severity as measured at day 15 postchallenge.

^fP < 0.001.