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. 2026 Aug 31;17:1826774. doi: 10.3389/fphar.2026.1826774

TABLE 2.

Effect of hesperetin on spleen histopathologic scoring in vincristine treated mice.

Comparison criteria Saline Vincristine Vincristine + HST HST per se
Cellularity of periarteriolar lymphoid sheaths 0 3.14 ± 0.69 1 ± 0.82 0
Lymphoid follicles 0 3.71 ± 0.49 2 ± 0.58 0
Marginal zone 0 3.85 ± 0.34 2.14 ± 0.69 0
Red pulp 0 2.71 ± 0.49 1.14 ± 0.69 0
Total number of germinal centers 0 2.43 ± 0.53 1.43 ± 0.53 0
Total score 0 15.86 ± 1.01* 7.71 ± 1.79 # 0

Data are the average scores for each group and SD.

*

versus the saline group.

#

Versus vincristine group at p < 0.05.