TABLE 2.
Effect of hesperetin on spleen histopathologic scoring in vincristine treated mice.
| Comparison criteria | Saline | Vincristine | Vincristine + HST | HST per se |
|---|---|---|---|---|
| Cellularity of periarteriolar lymphoid sheaths | 0 | 3.14 ± 0.69 | 1 ± 0.82 | 0 |
| Lymphoid follicles | 0 | 3.71 ± 0.49 | 2 ± 0.58 | 0 |
| Marginal zone | 0 | 3.85 ± 0.34 | 2.14 ± 0.69 | 0 |
| Red pulp | 0 | 2.71 ± 0.49 | 1.14 ± 0.69 | 0 |
| Total number of germinal centers | 0 | 2.43 ± 0.53 | 1.43 ± 0.53 | 0 |
| Total score | 0 | 15.86 ± 1.01* | 7.71 ± 1.79 # | 0 |
Data are the average scores for each group and SD.
versus the saline group.
Versus vincristine group at p < 0.05.