Table 3. Compilation of the potential sites identified by the library of delta ribozymes.
Cleavage position | HBV P1 stem | ORF targeteda | Rz pool assayb | Rz assayb |
---|---|---|---|---|
303 | GUGGUUU | C genes | ++ | +++ |
1365 | GUAAACC | Pre S2 | + | – |
1543 | GGACUUC | S genes | ++ | ++ |
2624 | GUUGUCC | P gene | + | ++ |
2833 | GUCUGUG | X gene | + | +++ |
2861 | GUGCACU | X gene | + | +++ |
aSee Figure 1B.
bRelative level of cleavage.