Table 2.

Comparison of NMSS and PDQ-39 domain scores among the total sample, early-stage, and mid-to-late-stage groups.

Domain	Total sample (N = 342)	Early-stage (n = 151)	Mid-to-late-stage (n = 191)	Z value	P value
Non-Motor Symptoms Scale (NMSS)
Cardiovascular (NMSS1)	2.00(0.00,2.00)	0.00(0.00,2.00)	2.00(0.00,4.00)	−6.15	<0.001
Sleep/fatigue (NMSS2)	8.00(4.00,12.00)	6.00(4.00,12.00)	8.00(5.00,12.00)	−3.08	0.002
Mood/cognition (NMSS3)	4.00(0.00,16.00)	2.00(0.00,8.00)	8.00(0.00,20.00)	−4.24	<0.001
Perceptual problems/hallucinations (NMSS4)	0.00(0.00,2.00)	0.00(0.00,0.00)	0.00(0.00,4.00)	−5.16	<0.001
Attention/memory (NMSS5)	2.00(0.00,4.00)	0.00(0.00,4.00)	4.00(0.00,6.00)	−5.01	<0.001
Gastrointestinal tract (NMSS6)	6.00(2.00,8.00)	2.00(2.00,6.00)	5.00(3.00,10.00)	−6.16	<0.001
Urinary (NMSS7)	4.00(0.00,6.00)	2.00(0.00,6.00)	6.00(0.00,6.00)	−3.75	<0.001
Sexual function (NMSS8)	0.00(0.00,1.00)	0.00(0.00,0.00)	0.00(0.00,1.00)	−0.29	0.779
Miscellaneous (NMSS9)	2.00(0.00,6.00)	2.00(0.00,6.00)	3.00(1.00,6.00)	−1.34	0.181
Parkinson’s Disease Questionnaire-39 (PDQ-39)
Mobility (PDQ1)	27.5(10.00,45.00)	15.00(2.50,35.00)	32.50(22.50,55.00)	−8.60	<0.001
Activities of daily living (PDQ2)	41.67(20.83,62.50)	27.50(12.50,50.00)	50.00(25.00,70.83)	−4.11	<0.001
Emotional well-being (PDQ3)	12.50(0.00,37.50)	8.33(0.00,33.33)	12.50(0.00,37.50)	−1.46	0.143
Stigma (PDQ4)	6.25(0.00,50.00)	6.25(0.00,50.00)	6.25(0.00,50.00)	−0.30	0.763
Social support (PDQ5)	0.00(0.00,8.33)	0.00(0.00,0.00)	0.00(0.00,16.67)	−1.46	0.144
Cognition (PDQ6)	25.00(12.50,37.50)	18.75(12.50,31.25)	31.25(18.75,43.75)	−6.14	<0.001
Communication (PDQ7)	0.00(0.00,16.67)	0.00(0.00,8.33)	8.33(0.00,16.67)	−5.06	<0.001
Bodily discomfort (PDQ8)	16.67(0.00,33.33)	16.67(0.00,25.00)	16.67(0.00,33.33)	−1.87	0.061

Values in bold indicate p < 0.05.