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. 2026 Sep 3;13:1933816. doi: 10.3389/fnut.2026.1933816

Table 2.

Multivariate-adjusted logistic regression models of TyG index and SUA for advanced CKM syndrome.

Variables Model1 Model2
OR (95%CI) P OR (95%CI) P
TyG
Per unit 1.59 (1.45 ~ 1.73) <0.001 1.81 (1.64 ~ 2.01) <0.001
Per SD 1.35 (1.28 ~ 1.43) <0.001 1.48 (1.38 ~ 1.58) <0.001
≤8.89 1.00 (Reference) 1.00 (Reference)
>8.89 1.81 (1.60 ~ 2.04) <0.001 1.95 (1.69 ~ 2.24) <0.001
TyG quantile
Q1 1.00 (Reference) 1.00 (Reference)
Q2 1.31 (1.08 ~ 1.58) 0.006 1.36 (1.09 ~ 1.69) 0.006
Q3 1.40 (1.16 ~ 1.69) <0.001 1.37 (1.10 ~ 1.70) 0.004
Q4 2.23 (1.87 ~ 2.67) <0.001 2.61 (2.13 ~ 3.21) <0.001
Ptrend <0.001 <0.001
SUA
Per 50 unit 1.22 (1.18 ~ 1.26) <0.001 1.20 (1.15 ~ 1.25) <0.001
Per SD 1.43 (1.35 ~ 1.52) <0.001 1.38 (1.28 ~ 1.48) <0.001
Non-HUA 1.00 (Reference) 1.00 (Reference)
HUA 1.82 (1.60 ~ 2.06) <0.001 1.86 (1.62 ~ 2.15) <0.001
SUA quantile
Q1 1.00 (Reference) 1.00 (Reference)
Q2 1.03 (0.84 ~ 1.26) 0.777 0.91 (0.72 ~ 1.14) 0.387
Q3 1.62 (1.35 ~ 1.96) <0.001 1.30 (1.05 ~ 1.61) 0.015
Q4 2.49 (2.08 ~ 2.97) <0.001 2.03 (1.64 ~ 2.50) <0.001
Ptrend <0.001 <0.001

Model 1 was unadjusted. Model 2 was adjusted for age, sex, ethnicity, educational level, marital status, smoking status, alcohol consumption, physical activity, nighttime sleep duration, and daytime napping. All covariates were prespecified and entered simultaneously using the enter method. All variance inflation factors were <2.0. TyG index, triglyceride-glucose index; SUA, serum uric acid; HUA, hyperuricemia; HUA, hyperuricemia; OR, odds ratio; CI, confidence interval.