TABLE 6.
Host range of LCMV-GP-pseudotyped retroviral vectors
| Cell line | Cell type | Pseudotype titera [TU/ml] (± SD) |
|---|---|---|
| Te671 | Fibroblast, human | 6.9 (± 2.0) × 105 |
| HeLa | Epithelial, cervix, human | 5.1 (± 2.4) × 105 |
| 293 | Epithelial, kidney, human | 9.4 (± 5.8) × 105 |
| nce-G112 | Glioma, human | 1.2 (± 5.9) × 106 |
| SH-SY | Neuroblastoma, human | 3.4 (± 1.3) × 105 |
| TF1 | Myeloid progenitor, human | 1.4 (± 8.9) × 104 |
| K562 | Myeloid progenitor, human | 1.8 (± 9.0) × 105 |
| HUH7 | Hepatoma, human | 3.5 (± 2.5) × 104 |
| CHO | Epithelial, ovary, hamster | 7.6 (± 6.1) × 104 |
| Cf2th | Thymus, canine | 2.8 (± 2.2) × 106 |
| SC1 | Fibroblast, embryo, mouse | 1.8 (± 4.2) × 106 |
a
Target cells were transduced with serial dilutions of LCMV-GP-pseudotyped oncoretroviral vector. Results are the mean vector titers and the standard deviations from three end-point dilutions.