TABLE 1.
MHCa class II allele | % Healthy controls (n = 43) | % All HCV (n = 58) | % Chronic HCV (n = 49) |
P
|
|
---|---|---|---|---|---|
All vs controls | Chronic vs controls | ||||
DRB1 | |||||
DRB1*01 | 4.9 | 10.2 | 10.2 | NS | NS |
DRB1*15 | 20.9 | 6.9 | 8.2 | 0.05 (pc = NS) | NS |
DRB1*16 | 9.3 | 8.2 | 8.2 | NS | NS |
DRB1*03 | 20.9 | 20.4 | 20.4 | NS | NS |
DRB1*04 | 23.4 | 34.7 | 34.7 | NS | NS |
DRB1*11 | 51.2 | 25.9 | 22.4 | 0.01 (pc = NS) | <0.008b |
DRB1*12 | 0 | 0 | 0 | NS | NS |
DRB1*13 | 14.0 | 32.8 | 32.7 | 0.05 (pc = NS) | NS |
DRB1*14 | 11.7 | 22.4 | 22.4 | NS | NS |
DRB1*07 | 21.0 | 22.4 | 22.4 | NS | NS |
DRB1*08 | 2.32 | 2.04 | 2.04 | NS | NS |
DRB1*10 | 0 | 2.04 | 2.04 | NS | NS |
DRB3* | 79.1 | 74.0 | 74.0 | NS | NS |
DRB4* | 39.5 | 53.1 | 53.1 | NS | NS |
DRB5* | 32.6 | 14.3 | 14.3 | NS | NS |
DQB1 | |||||
DQB1*02 | 37.2 | 36.7 | 36.7 | NS | NS |
DQB1*03 | 67.4 | 51.0 | 51.0 | NS | NS |
DQB1*04 | 2.3 | 2.0 | 2.0 | NS | NS |
DQB1*05 | 24.6 | 38.8 | 38.8 | NS | NS |
DQB1*06 | 23.5 | 36.7 | 36.7 | NS | NS |
MHC, major histocompatibility complex.
OR (95% confidence interval) = 0.276 (0.112-0.679).