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FIG. 2.

FIG. 2.

(A) Western blot of SAOS-pAW and SAOS-α2β1 cell homogenates without EV1 infection (C) or 0, 2, or 12 h p.i. (B) Binding of radioactively labeled EV1 onto SAOS-pAW and SAOS-α2β1 cells. (C) The proportional number of infected cells in SAOS-pAW and SAOS-α2β1 cells 10 h p.i. calculated after immunoperoxidase labeling. (D) The blocking effect of various antibodies on EV1 infection 10 h p.i. calculated after immunoperoxidase labeling (antibodies used in combination are 1950Z for anti-α2 and AB730 for anti-β2m). (E) Production of infectious EV1 in SAOS-α2β1 and SAOS-α2/α1β1 cells. The amount of intracellular virus in SAOS cells was determined in GMK cells as end point titers.