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. 2026 Aug 19;18(8):e114809. doi: 10.7759/cureus.114809

Table 1. Clinicopathological features of previously reported cases of MELTVR and the present case.

ER: estrogen receptor, PgR: progesterone receptor, EMA: epithelial membrane antigen, α-SMA: α smooth muscle actin, CK: Cytokeratin , AR: androgen receptor, +: positive, -: negative, NR: not reported

Author Age Clinical presentation Tumor size Histological findings Immunohistochemistry SMARCB1 Treatment Margin Outcome
Yoshida et al. [1] 24–70 Vulvar mass/nodule Variable Spindle to epithelioid cells with myxoid and hypercellular areas ER + PgR + EMA + variable α-SMA Lost Surgical excision Variable Mostly favorable (1-172 months)
Liu et al. [2] 43 Vulvar mass 3.5 cm Myxoid and solid components with spindle/plasmacytoid cells   Lost Wide local excision NR No recurrence
Urakami et al. [3] 54 Vulvar tumor after inguinal tumor excision 4 cm Lobulated tumor with myxoid stroma ER + PgR +   Lost Surgical excision Negative No recurrence (10 months)
Aminimoghaddam et al. [4] 46 Subcutaneous vulvar nodules with recent enlargement and discomfort; mass involving the right labia majora and mons pubis 10 cm Myxoid mesenchymal tissues. A mild to moderate atypia. No mitosis or necrosis Vimentin + Lost Surgical resection NR Recurrence (36 months)
Kamboj et al. [5] 47 A mobile swelling in the subcutaneous region of right labia majora 3 cm Solid sheets of cells with a predominant epithelioid to rhabdoid morphology and focal areas of spindling ER + EMA + CK - Lost Surgical resection NR No recurrence (6 months)
Present case 23 Myxoid and hypercellular areas with spindle to plasmacytoid cells, necrosis, and mitotic activity 4.5 cm Myxoid and hypercellular areas with spindle to plasmacytoid cells, necrosis, and mitotic activity ER + PgR + EMA + AR + Lost Surgical excision Negative No recurrence (3 months)