Table 1.
Descriptive characteristics of 10,434 metastatic medullary and clear cell RCC in the SEER database 2000–2021 according to histological subtype and receipt of cytoreductive nephrectomy, before and after 1:3 propensity score matching
| Characteristic | Before PSM | After 1:3 PSM | ||||||
|---|---|---|---|---|---|---|---|---|
| Overall n = 10,434 |
Medullary RCC n = 62 (0.6%)1 |
Clear cell RCC n = 10,372 (99.4%)1 |
p-value | Overall n = 248 |
Medullary n = 62 (25%)1 |
Clear cell RCC n = 186 (75%)1 |
p-value | |
| Age | 63 (56, 71) | 27 (22, 35) | 63 (56, 71) | < 0.001 | 50 (38, 55) | 27 (22, 35) | 53 (47, 57) | < 0.001 |
| Male sex | 7149 (69%) | 45 (73%) | 7104 (68%) | 0.5 | 174 (70%) | 45 (73%) | 129 (69%) | 0.6 |
| T Stage | 0.3 | 1.0 | ||||||
| T1-2 | 2087 (20%) | 16 (26%) | 2071 (20%) | 64 (26%) | 16 (26%) | 48 (26%) | ||
| T3-4 | 8347 (80%) | 46 (74%) | 8301 (80%) | 184 (74%) | 46 (74%) | 138 (74%) | ||
| N Stage | < 0.001 | 1.0 | ||||||
| N0/Nx | 7474 (72%) | 30 (48%) | 7444 (72%) | 120 (48%) | 30 (48%) | 90 (48%) | ||
| N1 | 2960 (28%) | 32 (52%) | 2928 (28%) | 128 (52%) | 32 (52%) | 96 (52%) | ||
| Race | < 0.001 | 1.0 | ||||||
| Caucasian | 7305 (70%) | 3 (5%) | 7302 (70%) | 12 (5%) | 3 (5%) | 9 (5%) | ||
| African American | 669 (6%) | 46 (74%) | 623 (6%) | 184 (74%) | 46 (74%) | 138 (74%) | ||
| Other | 2460 (24%) | 13 (21%) | 2447 (24%) | 52 (21%) | 13 (21%) | 39 (21%) | ||
| CN | 0.2 | 0.6 | ||||||
| Yes | 5939 (57%) | 30 (48%) | 5909 (57%) | 127 (51%) | 30 (48%) | 97 (52%) | ||
Abbreviations:PSMpropensity score matching,CN cytoreductive nephrectomy, RCC renal cell carcinoma
1Median (Q1, Q3);n(%)