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. 2026 Sep 19;44(1):680. doi: 10.1007/s00345-026-06587-8

Table 3.

Multivariable Cox regression models addressing overall survival in (a) metastatic medullary RCC and (b) metastatic clear cell RCC (SEER 2000–2021) according to receipt of cytoreductive nephrectomy

Characteristic Univariable Multivariable*
HR1 95% CI1 p-value HR1 95% CI1 p-value
(a) Metastatic medullary RCC
CN (Ref: no CN)
 CN performed 0.5 0.3, 0.9 0.016 0.5 0.3, 0.9 0.019
(b) Metastatic ccRCC
CN (Ref: no CN)
 CN performed 0.4 0.3, 0.6 < 0.001 0.4 0.3, 0.5 < 0.001

1HR Hazard Ratio, CI  Confidence Interval, CN cytoreductive nephrectomy

*Adjusted for age, sex, race

Bold values are the p-values, they are highlighted due to statistically significance.