TABLE 1.

Summary of M1 and M2 mutant phenotypes^a

Virus	Mean virus titer (PFU) in spleen, day 9	Latencyb in spleen								Latency in PECs
		Day 16 (i.n.)		Day 16 (i.p.)		Day 42 (i.n.)		Day 42 (i.p.)		Day 42 (i.p.)
		RF	GF	RF	GF	RF	GF	RF	GF	RF	GF
wt γHV68	1,466	1/9,000	1/100	1/60,000	1/450	<<1/105	1/3,000	<1/105	1/1,500	1/10,000c-1/12,000	1/600c-1/1,000
M2.LacZ	<50	<1/105	1/2,500	1/60,000	ND	ND	ND	<1/105	1/1,500	1/800	ND
M2.Stop	<50	<1/105	1/1,000	≈1/105	1/300	<<1/105	1/3,000	<1/105	1/500	1/6,000	1/1,000
M1.LacZc	<50c	ND	ND	ND	ND	ND	ND	<1/105	ND	1/700c	1/300c
M1.Δ511c	2,070c	ND	ND	ND	ND	ND	ND	<1/105	ND	1/1,000c	ND

^aAbbreviations: i.n., intranasal inoculation; i.p., intraperitoneal inoculation; RF, frequency of cells reactivating latent γHV68; GF, frequency of cells harboring the γHV68 genome; ND, not determined.

^bFrequency of cells harboring and reactivating virus.

^cData are from reference 1.