Figure 5.

Regeneration of normal capillary tissue by ACE inhibition in Munich Wistar Fromter rats. Distribution of normal (nonsclerosed) capillary tissue as estimated by serial section reconstruction of the entire capillary tuft in Munich Wistar Fromter rats at 50 weeks of age, in untreated rats at 60 weeks of age, and in animals treated with an ACE inhibitor (ACEi; lisinopril) from 50–60 weeks of age. One hundred glomeruli have been completely reconstructed in each animal group, and values of nonsclerosed volume represented in ascending order. Numbers in the abscissa represent reconstructed glomerular capillary tufts. Data obtained by elaboration of experimental results described in ref. 108.