Diagram of the interactions of gene products of HSV-1 and PrV involved in virion formation. Solid lines or direct contacts between the rectangles representing the designated gene products indicate physical interaction, whereas arrows indicate functional effects. Dotted lines and question marks denote suggested, but not firmly established, interactions or involvement of proteins. Between glycoproteins, only direct contacts resulting in complex formation are depicted. Steps: 1, primary envelopment; 2, de-envelopment; 3, secondary (final) envelopment. NUC, nucleus; CYT, cytoplasm.