TABLE 4.
Statistical analysis of checkerboard results
| Seruma | Virusesa |
P derived fromb:
|
|
|---|---|---|---|
| Positive response rate | Mean NAb titer | ||
| Du | Du vs B | 0.03 | 0.31 |
| B | Du vs B | 0.13 | 0.13 |
| Du | Mw vs B | 0.19 | 0.50 |
| Du | Du vs Mw | 0.25 | 0.13 |
a
Du, clade C from South Africa; B, clade B; Mw, clade C from Malawi.
b
Overall differences in either the positive neutralization response rate or mean log neutralizing antibody (NAb) titers between genetic subtypes of the virus were tested for significance by using the nonparametric Wilcoxon sign rank test. Differences were considered significant if P was ≤0.05. To eliminate bias, results of autologous serum-virus pairs in the Du samples were excluded from analysis, since this was the only group where autologous pairs were present.