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. 2026 Jun 20;4(9):2150–2157. doi: 10.1021/envhealth.6c00088

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Uptake of six tested PFAS by wild-type HEK293 cells (empty bar), human OAT1-transfected HEK293 cells (solid bar), and net uptake (bar with diagonal lines). Each bar represents mean ± SD of triplicates. The asterisk (*) in the figure indicates a significant difference in PFAS uptake between wild-type HEK293 cells and human OAT1-transfected HEK293 cells. Note that uptake experiments were performed with PFOA, HFPO-DA, HFPO-TA, and PFOS at 10 μmol/L for 10 min, while for 9Cl-PF3ONS and 11Cl-PF3OUdS (indicated by light purple shading), the concentration was 4 μmol/L for 10 min due to their low solubilities in water.