Table 6.
XGBoost ensemble performance on known antibiotic classes for the second approach.
| Antibiotic target class | Index | Precision | Recall | F1-Score | Support |
|---|---|---|---|---|---|
| 30S ribosomal subunit | 0 | 0.88 | 1.00 | 0.93 | 14 |
| 50S ribosomal subunit | 1 | 1.00 | 0.84 | 0.91 | 19 |
| DNA | 2 | 1.00 | 1.00 | 1.00 | 1 |
| DNA gyrase | 3 | 1.00 | 1.00 | 1.00 | 16 |
| DNA-directed RNA polymerase subunit β | 4 | 1.00 | 1.00 | 1.00 | 2 |
| Lipopolysaccharide | 5 | 1.00 | 1.00 | 1.00 | 1 |
| UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 6 | 1.00 | 1.00 | 1.00 | 1 |
| β-lactamases | 7 | 1.00 | 0.50 | 0.67 | 2 |
| Dihydrofolate reductase | 8 | 1.00 | 1.00 | 1.00 | 2 |
| Dihydrofolate synthase | 9 | 1.00 | 1.00 | 1.00 | 9 |
| Enoyl-[acyl-carrier-protein] reductase (NADH) | 10 | 0.00 | 0.00 | 0.00 | 0 |
| Ionophore | 11 | 0.86 | 0.86 | 0.86 | 7 |
| Penicillin binding protein | 12 | 0.93 | 1.00 | 0.97 | 28 |
| Peptidoglycan (D-Ala-D-Ala) | 13 | 1.00 | 1.00 | 1.00 | 2 |
| Average | 0.96 | 0.95 | 95 |
Individual values are given for known antibiotic categories curated from the KEGG database.