(A) (Top) Pyrimidine content of the first 129 nucleotides of the wild-type (wt) and mutant (MUT) HPV-16 L1 gene sequences. (Bottom) AU contents of the first 129 nucleotides of the wild-type and mutant HPV-16 L1 gene sequences. (B) Sequence alignments of the first 129 nucleotides of the L1 gene coding sequences of HPV-5, HPV-6b, HPV-16, HPV-18, HPV-31, HPV-45, and HPV-56 and the mutant HPV-16 L1 gene sequence. Regions A, B, and C are discussed in Discussion.