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Replication of recombinant RSV in mice and cotton rats
| Virus | Virus titer in lungs (mean log10 PFU/g ± SE)a in:
|
|
|---|---|---|
| Mice | Cotton rats | |
| rA2 | 4.64 ± 0.08 | 4.72 ± 0.08 |
| rA2-P172 | 1.97 ± 0.99 | 3.29 ± 0.39 |
| rA2-P176 | 0.90 ± 1.20 | 2.21 ± 0.11 |
Groups of eight BALB/c mice or cotton rats were inoculated with 106 PFU of virus intranasally under light anesthesia on day 0 and sacrificed on day 4. Virus titers from the lung tissues were determined by plaque assay.
