TABLE 1.
Statistically significant experimental variation of the intrahepatic content of HBV replicative forms in mice heterozygous (plus/minus) or homozygous (minus/minus) for the IRF-1 or PKR null mutationa
Mouse | Ratio for the following mice:
|
|||
---|---|---|---|---|
IRF-1+/− | IRF-1−/− | PKR+/− | PKR−/− | |
1 | 78 | 104 | 47 | 68 |
2 | 52 | 91 | 58 | 47 |
3 | 67 | 88 | 36 | 54 |
4 | 48 | 102 | 34 | 71 |
5 | 56 | 107 | 61 | 78 |
6 | 44 | 77 | 74 | |
7 | 48 | |||
Mean ± SD | 56.1 ± 12 | 94.8 ± 11 | 47.2 ± 12 | 63.6 ± 11 |
Data represent the ratio between the values obtained by phosphorimaging analysis for HBV replicative forms and the transgene.