TABLE 1.

Amino acid changes in the Sendai virus L mutants

Mutant	Amino acid changesa	P bindingb
SV 514	L20A, S22A, I24A, V25A	−
SV 515	T29A, Q31A, L32A, H33A	−
SV 516	Q77A, R78S, T79A, K81A	±
SV 517	F173A, L174A, T175A, F177A	−
SV 518	Y209A, L210E, T211A, V212A, T213A	−
SV 519	L235A, V236A, L237A, M238A	−
SV 520	L262A, L263A, V264G, K265R, G266A	±
SV 521	V287A, I288A, L290A, L291A	−
SV 522	I345A, F346A, H347A	−

^aChanges are indicated as the amino acid position in the Sendai virus L protein. The letter preceding the position is the wt sequence, and the amino acid to which it was changed appears after the number. Domain I in Sendai virus L extends from aa 225 to 416.

^bSummary of Sendai virus L mutant binding to P from Fig. 1 and 2; ±, 10 to 20% of wt L; −, no detectable binding.