4-1BB	4-1BB receptor (CD137; TNFRSF9)
4-1BBL	4-1BB ligand (TNFSF9)
aa	Amino acid(s)
ADCC	Antibody-dependent cellular cytotoxicity
AML	Acute myeloid leukemia
AP-1	Activator protein 1
APC	Antigen-presenting cell
ATL	Adult T-cell leukemia/lymphoma
BCR	B-cell receptor
BTLA	B- and T-lymphocyte attenuator
CAR-T	Chimeric antigen receptor T cell
CD	Cluster of differentiation
CEACAM1	Carcinoembryonic antigen-related cell adhesion molecule 1
CRD	Cysteine-rich domain
CTLA-4	Cytotoxic T-lymphocyte-associated protein 4
CVID	Common variable immunodeficiency
Da	Dalton
DC	Dendritic cell
DNAM-1	DNAX accessory molecule-1 (CD226)
EMT	Epithelial–mesenchymal transition
ERK	Extracellular signal-regulated kinase
FcγR	Fc gamma receptor
FGL1	Fibrinogen-like protein 1
GITR	Glucocorticoid-induced TNFR-related protein
GITRL	Glucocorticoid-induced TNFR-related protein ligand
GVHD	Graft-versus-host disease
HAVCR2	Hepatitis A virus cellular receptor 2
HMGB1	High mobility group box 1
HVEM	Herpesvirus entry mediator
ICOS	Inducible T-cell costimulator
ICOSL	Inducible T-cell costimulator ligand
IFN-γ	Interferon gamma
IgSF	Immunoglobulin superfamily
IL	Interleukin (e.g., IL-2, IL-10, IL-12)
ICP	Immune checkpoint
irAEs	Immune-related adverse events
ITIM	Immunoreceptor tyrosine-based inhibitory motif
ITSM	Immunoreceptor tyrosine-based switch motif
ITT-like	Immunoreceptor tyrosine-based inhibitory motif-like motif
LAG-3	Lymphocyte activation gene 3
LFA-3	Lymphocyte function-associated antigen 3 (CD58)
LIGHT	Homologous to lymphotoxins, exhibits inducible expression, competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes
MAPK	Mitogen-activated protein kinase
MDSCs	Myeloid-derived suppressor cells
MHC	Major histocompatibility complex
mAb	Monoclonal antibody
NECTIN2	Nectin cell adhesion molecule 2
NFAT	Nuclear factor of activated T cells
NK	Natural killer cell
OX40	OX40 receptor (TNFRSF4)
OX40L	OX40 ligand (TNFSF4)
PBMC	Peripheral blood mononuclear cells
PD-1	Programmed cell death protein 1
PD-L1	Programmed death-ligand 1
PD-L2	Programmed death-ligand 2
PI3K/AKT	Phosphoinositide 3-kinase/Protein kinase B signaling pathway
pI	Theoretical isoelectric point
PSGL-1	P-selectin glycoprotein ligand-1
PtdSer	Phosphatidylserine
PVR	Poliovirus receptor
PVRIG	Poliovirus receptor-related immunoglobulin domain-containing protein
ROS	Reactive oxygen species
SELPLG	Selectin P ligand gene
TAM	Tumor-associated macrophage
TCR	T-cell receptor
Tfh	T follicular helper cell
TIGIT	T-cell immunoreceptor with Ig and ITIM domains
TILs	Tumor-infiltrating lymphocytes
TIM-3	T-cell immunoglobulin and mucin-domain containing-3
TLS	Tertiary lymphoid structures
TMB	Tumor mutational burden
TME	Tumor microenvironment
TNF	Tumor necrosis factor
TNFRSF	Tumor necrosis factor receptor superfamily
TNFSF	Tumor necrosis factor superfamily
TRAF1	TNF receptor-associated factor 1
TRAF2	TNF receptor-associated factor 2
TRAF3	TNF receptor-associated factor 3
Treg	Regulatory T cell
VISTA	V-domain Ig suppressor of T-cell activation
VSIR	V-set immunoregulatory receptor